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小柴朴汤治疗感染后咳嗽临床观察OA

Xiaochaipo Decoction in treating Post-infectious Cough

中文摘要英文摘要

目的 探讨小柴朴汤治疗痰湿阻肺型感染后咳嗽的临床疗效.方法 选择2022年6月—2025年6月在泉州市丰泽街道社区服务中心就诊的102例感染后咳嗽患者,按随机数字表法分为观察组(51例)和对照组(51例).对照组予以复方甲氧那明治疗,观察组在对照组基础上加用小柴朴汤治疗,对比2组的临床疗效及中医证候积分、咳嗽起效时间、咳嗽症状积分、咳嗽视觉模拟量表(VAS)评分、简易咳嗽程度评分表(CET)评分、莱切斯特咳嗽生活质量问卷(LCQ)及血清肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平.结果 观察组临床疗效高于对照组(P<0.05).治疗后,观察组中医证候积分、咳嗽症状积分、VAS评分、CET评分及血清TNF-α和IL-6水平均低于对照组(P<0.05),咳嗽起效时间短于对照组(P<0.05),LCQ评分高于对照组(P<0.05).2组不良反应比较,差异无统计学意义(P>0.05).结论 小柴朴汤能有效缓解痰湿阻肺型感染后咳嗽患者临床症状,减轻炎症反应,从而有助于生活质量的提高,且不会增加不良反应,值得临床推广应用.

Objective To discuss the clinical efficacy of Xiaochaipo decoction in treating post-infectious cough of phlegm-dampness obstructing lung type.Methods One hundred and two patients with post-infection cough in Fengze Subdistrict Community Health Service Center of Fengze District from June 2022 to June 2025 were randomly divided into observation group(51 cases)and control group(51 cases).The control group was treated with compound Methoxyphenamine,and the observation group was treated with Xiaochaipo decoction on the basis of the control group.The clinical efficacy,traditional Chinese medicine(TCM)syndrome score,cough onset time,cough symptom score,cough visual analogue scale(VAS)score,simple cough scale(CET)score,Leicester cough quality of life questionnaire(LCQ),serum tumor necrosis factor-α(TNF-α)and interleukin-6 were compared between the two groups.Results The clinical efficacy of the observation group was higher than that of the control group(P<0.05).After treatment,the TCM syndrome score,cough symptom score,VAS score,CET score,serum TNF-α and IL-6 in the observation group were lower than those in the control group(P<0.05),the onset time of cough was shorter than that in the control group(P<0.05),and the LCQ score was higher than that in the control group(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Xiaochaipo decoction could effectively relieve clinical symptoms,alleviate inflammatory responses in patients with post-infectious cough of phlegm-dampness obstructing the lung type,thereby improving their quality of life,which does not increase adverse reactions and is worthy of clinical promotion and application.

孔发英;郑晓军

泉州市丰泽区丰泽街道社区卫生服务中心全科医学科,福建 泉州 362000泉州市中医院内科,福建 泉州 362000

医药卫生

感染后咳嗽痰湿阻肺证小柴朴汤复方甲氧那明中医药疗法

post-infectious coughphlegm-dampness obstructing lung syndromeXiaochaipo decoctioncompound Methoxyphenaminetherapy of traditional Chinese medicine

《光明中医》 2026 (7)

25-29,5

福建省第二批基层老中医药专家学术继承项目(No.闽卫中医函[2022]1222号)

10.70976/j.issn.1003-8914.2026.07.005

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