Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9OA
Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9
Yaqiang Hu;Zhiyang Zeng;Xinyu Ming;Shuming Yin;Yuting Guan;Liangcai Gao;Dali Li
Shanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,ChinaFengxian Central Hospital Affiliated to Southern Medical University,Shanghai,ChinaShanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,ChinaShanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,ChinaShanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,ChinaShanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,ChinaShanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,China
CRISPR/Cas9endoplasmic reticulum stressmouse modelneurodegenerative diseasesSec16a
CRISPR/Cas9endoplasmic reticulum stressmouse modelneurodegenerative diseasesSec16a
《动物模型与实验医学（英文）》 2026 (3)
537-545,9
The Chunhui Program of the ministry of Education,Grant/Award Number:HZKY20220076the Shanghai Municipal Commission of Science and Technology,Grant/Award Number:21JC1402200,22YF1437700 and 23HC1400700National Natural Science Foundation of China,Grant/Award Number:32200732National Key Research and Development Program of China,Grant/Award Number:2022YFC3400200
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