后路寰枢椎融合与非融合术治疗老年齿状突Ⅱ型骨折的短期与中期疗效分析OA
Short-term and mid-term efficacy analysis of posterior atlantoaxial fusion and non-fusion surgery in the treatment of elderly type Ⅱ odontoid fractures
目的 比较后路寰枢椎融合术与非融合术治疗老年齿状突Ⅱ型骨折的短期与中期疗效,为临床治疗提供依据.方法 选取2021年1月至2023年12月在该院接受手术治疗的60例老年齿状突Ⅱ型骨折患者为研究对象,采用随机数字表法分为融合组与非融合组,每组各30例.融合组行后路寰枢椎椎弓根螺钉固定联合自体髂骨植骨融合术,非融合组仅行螺钉系统固定.两组术后均佩戴颈托外固定12周,随访12~17个月.比较两组基线资料、手术相关指标及骨折愈合情况;于术前及术后3、6、9、12个月评估疼痛视觉模拟量表(VAS)评分及日本骨科学会(JOA)评分;于骨折愈合后3个月(融合组)或取出内固定后3个月(非融合组)评估颈椎功能障碍指数(NDI)及颈椎活动度.结果 术后两组 VAS评分随时间明显改善(F=798.00,P<0.05),融合组术后12个月VAS评分改善程度优于非融合组(P=0.009),其余各时间点两组VAS评分改善程度比较,差异无统计学意义(P>0.05).两组JOA 评分随时间呈非线性改善,时间主效应显著(F=186.34,P<0.001),术后3~6个月改善最为明显;术后9个月非融合组JOA评分改善程度优于融合组(P=0.046),其余时间点两组JOA评分改善程度比较,差异无统计学意义(P>0.05).两组骨性愈合率、纤维性愈合率、骨不愈合率及骨折愈合时间差异无统计学意义(P>0.05).术后,非融合组NDI评分低于融合组,颈椎活动度高于融合组(P<0.001).非融合组C1~C2 融合率为96.7%(29/30),评估者间一致性良好(Kappa=0.82).结论 后路寰枢椎融合术与非融合术治疗老年齿状突Ⅱ型骨折均可获得满意的疼痛缓解及神经功能恢复效果,非融合术在保留颈椎活动度及降低功能障碍方面具有明显优势,对于适合的老年患者可作为有效的治疗选择.
Objective To compare the short-term and mid-term therapeutic effects of posterior atlanto-axial fusion surgery and non-fusion surgery in the treatment of elderly type Ⅱ odontoid fractures,and to guide clinical decision-making.Methods Sixty elderly patients with type Ⅱ odontoid fractures who underwent sur-gical treatment in this hospital from January 2021 to December 2023 were selected as the research subjects.They were randomly divided into the fusion group and the non-fusion group using a random number table,with 30 cases in each group.The fusion group underwent posterior atlantoaxial pedicle screw fixation com-bined with autologous iliac bone graft fusion surgery,while the non-fusion group underwent screw fixation a-lone.Both groups wore cervical collars for external fixation for 12 weeks after surgery,and were followed up for 12 to 17 months.The baseline data,surgical-related indicators,and fracture healing conditions of the two groups were compared;the Visual Analogue Scale(VAS)score and the Japanese Orthopaedic Association(JOA)score were evaluated before surgery and at 3,6,9,and 12 months after surgery;the Cervical Disability Index(NDI)and cervical range of motion were evaluated 3 months after fracture healing(in the fusion group)or 3 months after removal of internal fixation(in the non-fusion group).Results VAS scores improved sig-nificantly over time in both groups(F=798.00,P<0.05);the fusion group showed greater improvement at 12 months(P=0.009),but no significant differences were observed at other time points(P>0.05).JOA scores improved non-linearly over time in both groups,with a significant time effect(F=186.34,P<0.001);the most pronounced improvement occurred between 3 and 6 months.The non-fusion group showed greater JOA improvement at 9 months(P=0.046),with no significant differences at other time points(P>0.05).No significant between-group differences were observed in bone healing rate,fibrous union,nonunion,or frac-ture healing time(P>0.05).Postoperatively,the non-fusion group had a lower NDI score and greater cervical range of motion than the fusion group(both P<0.001).The C1-C2 fusion rate in the non-fusion group was 96.7%(29/30),with good inter-rater agreement(Kappa=0.82).Conclusion Both posterior atlantoaxial fu-sion and non-fusion surgery provide satisfactory pain relief and neurological recovery in elderly patients with type Ⅱ odontoid fractures.Non-fusion surgery offers significant advantages in preserving cervical mobility and reducing functional disability,and may serve as an effective option for suitable elderly patients.
石现;刘昭静;何秦
达州市中心医院骨科,四川 达州 635000达州市中心医院骨科,四川 达州 635000达州市中心医院骨科,四川 达州 635000
医药卫生
齿状突骨折老年患者融合术非融合术临床疗效
odontoid fractureelderly patientsfusion surgerynon-fusion surgeryclinical efficacy
《重庆医学》 2026 (6)
1321-1326,1333,7
四川省达州市科技局重点研发项目(22ZDYF0012).
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