基于"血浊理论"探讨妇科瘀证"浊-瘀-毒"病机演变规律及辨治要点OA
Exploring the pathogenesis evolution law of"turbidity-stasis-toxin"and the key points of syndrome differentiation and treatment for gynecological blood stasis syndrome based on"blood turbidity theory"
"血浊理论"是在血液病理层面揭示代谢性及复杂性疾病病机演变规律的原创理论,本文将该理论引入妇科疾病的治疗中,并与齐鲁妇科流派所倡导的瘀毒学说相贯通,旨在构建"浊-瘀-毒"动态传变的整合病机模式.本团队认为,在浊、瘀、毒的作用下,妇科疾病多呈现因浊致瘀、瘀久酿毒的核心病理演变规律.女性以肝血为用,以冲任为系,血浊内蕴实为瘀证形成的关键基础.浊邪壅滞胞络,初则碍气,渐而凝瘀,终成癥瘕;瘀血久羁,郁而化热,腐损络脉,遂生毒邪,以致病情深痼、缠绵反复.基于此,本团队提出妇科之瘀证当以澄源清流、分期论治为纲,确立以化浊为枢机,贯穿始终的治疗策略,强调非独攻已成之瘀,尤重清化未形之浊,以截断传变、防其复发."血浊理论"不仅可为子宫内膜异位症、子宫腺肌病、多囊卵巢综合征等妇科疾病提供新的理论阐释与分期辨治框架,亦体现内科理论与妇科专病理论之深度融合与学术创新.
The original"blood turbidity theory"reveals the evolutionary patterns of disease mechanisms underlying metabolic and complex diseases at the blood pathology level.This paper introduces this theory into the treatment of gynecological diseases.It integrates it with the"stasis-toxin"doctrine advocated by the Qilu gynecology school,aiming to construct an integrated disease mechanism model of the dynamic transformation of"turbidity-stasis-toxin".Our team holds that under the influence of turbidity,stasis,toxin,gynecological diseases mostly exhibit the core pathological evolutionary pattern of stasis resulting from turbidity,and toxin brewing from prolonged stasis.Women depend on liver blood for physiological function and are connected by the thoroughfare and conception channels;thus,internal accumulation of blood turbidity is the critical foundation for the formation of stasis syndrome.When turbidity pathogens stagnate in the uterine collaterals,they initially hinder qi,gradually condense into stasis,and eventually form pelvic masses.When stasis blood is detained for extended periods,stagnation transforms into heat,corroding and damaging the collaterals,thereby generating toxic pathogens,leading to deep-seated,lingering,and recurrent conditions.Based on this,our team proposes that stasis syndrome in gynecology should follow the guideline of clarifying the source and clearing the flow along with stage-based treatment,establishing a treatment strategy of taking turbidity resolution as the pivot throughout the entire process.We emphasize not only attacking the already-formed stasis but especially focusing on clearing and transforming the yet-unformed turbidity to intercept transmission and prevent recurrence.The"blood turbidity theory"provides a new theoretical explanation and a stage-based differentiation and treatment framework for gynecological diseases such as endometriosis,adenomyosis,and polycystic ovary syndrome,and embodies the deep integration and academic innovation between internal medicine theories and gynecological-specific disease theories.
甄佳;王文成;赵紫渊;王子璐;徐丽;王新陆;师伟
山东中医药大学第一临床医学院 济南 250014山东中医药大学第一临床医学院 济南 250014山东中医药大学第一临床医学院 济南 250014山东中医药大学第一临床医学院 济南 250014山东中医药大学第二附属医院生殖科山东中医药大学山东中医药大学附属医院妇科
医药卫生
血浊瘀证癥瘕瘀毒
blood turbidityblood stasis syndromepelvic massstasis-toxin
《北京中医药大学学报》 2026 (6)
829-833,5
国家自然科学基金项目(No.82474559) National Natural Science Foundation of China(No.82474559)
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