中国传统功法对慢性心力衰竭患者运动及心功能疗效的网状Meta分析OA
A Network Meta-Analysis of the Efficacy of Traditional Chinese Exercises on Exercise Capacity and Cardiac Function in Patients with Chronic Heart Failure
目的:采用网状Meta分析评价不同功法改善慢性心力衰竭患者运动及心功能的疗效,探讨最佳传统功法方案.方法:检索中国知网、万方、维普、及Web of Science、PubMed、Cochrane Library、EMbase数据库中关于中国传统功法改善慢性心力衰竭患者运动及心功能的随机对照试验,采用Cochrane协作网推荐的偏倚风险评估工具对纳入的文献进行质量评价,采用Revman5.4和Stata 17.0对4个结局指标(6 min步行测试、峰值摄氧量、N端脑利肽前体、左心室射血分数)进行网状Meta分析.结果:①最终纳入35项随机对照试验,涉及5种传统功法,包括太极拳、六字诀、五禽戏、八段锦以及太极拳联合八段锦.②网状Meta分析结果显示:与常规治疗相比,太极拳[MD=68.27,95%CI=(43.37,93.17),P<0.05]在改善慢性心力衰竭患者6 min步行距离的疗效最佳;在改善峰值摄氧量方面,八段锦[MD=2.27,95%CI=(1.20,3.33),P<0.05]的疗效最佳;在改善N端脑利肽前体方面,八段锦[SMD=-1.35,95%CI=(-2.31,-0.39),P<0.05]的疗效最佳;在改善患者左心室射血分数方面,八段锦[MD=4.75,95%CI=(3.31,6.18),P<0.05]的疗效最佳.结论:中国传统功法在改善慢性心力衰竭患者运动及心功能方面具有显著疗效.其中,在改善6WMD方面,太极拳的疗效最佳;在改善peak VO2方面,八段锦的疗效最佳;在改善NT-proBNP方面,八段锦的疗效最佳;在改善LVEF方面,八段锦的疗效最佳.
Objective:This study aimed to evaluate the comparative efficacy of different TCEs on improving exercise capacity and cardiac function in patients with CHF through a network meta-analysis,and to identify the optimal TCE regimen.Methods:A computerized search was conducted for randomized controlled trials(RCTs)on the effects of TCEs on exercise capacity and cardiac function in patients with CHF.Searched databases included CNKI,WanFang Data,VIP Database,Web of Science,PubMed,Cochrane Library,and Embase.The methodological quality of the included literature was assessed using the Cochrane Collaboration's tool for assessing risk of bias.A network meta-analysis was performed using Revman5.4 and Stata 17.0 to analyze four outcome measures:the 6-Minute Walk Test(6MWT),peak oxygen uptake(peak VO2),N-terminal pro-B-type natriuretic peptide(NT-proBNP),and left ventricular ejection fraction(LVEF).Results:A total of 35 RCTs were ultimately included,involving five types of TCEs:Tai Chi,Liuzijue,Wuqinxi,Baduanjin,and Tai Chi combined with Baduanjin.The network meta-analysis results indicated that compared to conventional therapy,Tai Chi was the most effective intervention for improving the 6-Minute Walk Distance(6MWD)in patients with CHF[MD=68.27,95%CI(43.37,93.17),P<0.05].Baduanjin was identified as the most effective intervention for improving peak VO2[MD=2.27,95%CI(1.20,3.33),P<0.05],reducing NT-proBNP levels[SMD=-1.35,95%CI(-2.31,-0.39),P<0.05],and increasing LVEF[MD=4.75,95%CI(3.31,6.18),P<0.05].Conclusion:Traditional Chinese Exercises are significantly effective in improving exercise capacity and cardiac function in patients with CHF.Among the interventions analyzed,Tai Chi is optimal for improving the 6MWD,while Baduanjin demonstrates the best efficacy in improving peak VO2,reducing NT-proBNP levels,and increasing LVEF.
刘瑶;左杨瑞;王刚;刘时璋
西安体育学院,陕西 西安 710068西安体育学院,陕西 西安 710068西安体育学院,陕西 西安 710068陕西省人民医院,陕西 西安 710068
医药卫生
慢性心力衰竭传统功法6 min步行测试峰值摄氧量N端脑利肽前体左心室射血分数网状Meta分析
chronic heart failureTraditional Chinese exercises6-minute walk testpeak VO2NT-proBNPLVEFnetwork meta-analysis
《中医康复》 2026 (7)
1-12,12
陕西省科技厅项目(2025JC-GXPT-039)
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