基于"主客交"理论探讨系统性硬化症的病机及辨治思路OA
Exploring the Pathogenesis and Treatment Strategies of Systemic Sclerosis Based on the"Subject-Object Interaction"Theory
"主客交"理论由温病大家吴又可在《瘟疫论》中提出,起初以治疗瘟疫病为主,经后世医家继承与发展,理论延伸至正虚邪恋、胶结难愈之慢性病的治疗."主客交"中"主"为人体正气,"客"为外来或内生病邪,"主客交"的核心在于正虚邪客,邪气不得外解,与血脉相胶结,形成痼疾.系统性硬化症为素体脾肾阳虚,外邪入侵,交争于肌表、血脉、脏腑,久则痰瘀内生,脉络凝瘀,与"主客交"理论密切相关.基于此,提出补主逐客、通络解交之法治疗系统性硬化症.
The"Host-Pathogen Interaction"theory was proposed by the renowned physician WU Youxian in his work"On Pestilence".Initially,it was mainly used for treating epidemic diseases.Later,through the inheritance and development by subsequent medical practitioners,the theory extended to the treatment of chronic diseases with de-ficiency of the body's vital energy and coexisting pathogenic factors,which are difficult to heal.The core of"Host-Pathogen Interaction"lies in the deficiency of the body's vital energy and the intrusion of pathogenic factors,which cannot be expelled externally and are intertwined with the blood vessels,forming stubborn diseases.Systemic sclerosis is characterized by a congenital deficiency of the spleen and kidney yang,and the invasion of external pathogens,which compete with each other on the skin,blood vessels,and internal organs.Over time,phlegm and blood stasis are gen-erated internally,and the blood vessels become congested and filled with blood stasis,which is closely related to the"Host-Pathogen Interaction"theory.Based on this,the method of tonifying the host and expelling the guest,and un-blocking the meridians and resolving the interaction is proposed for the treatment of systemic sclerosis.
张子豪;郭静秋;陈聪;林雯雯;黄上;朱克俭;郑燕姣;胡梁;刘劲松
湖南中医药大学 湖南 长沙 410208||湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南中医药大学 湖南 长沙 410208||湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南中医药大学 湖南 长沙 410208||湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南中医药大学 湖南 长沙 410208||湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006湖南省中西医结合医院,湖南省中医药研究院附属医院 湖南 长沙 410006
医药卫生
主客交系统性硬化症病机辨治
Host-Invader interactionSystemic sclerosisPathogenesisDiagnosis and treatment
《中医药临床杂志》 2026 (6)
1110-1114,5
湖南省自然科学基金,医卫联合(2024JJ50245)
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