体外冲击波穴位疗法联合独活寄生汤治疗寒湿痹阻型膝骨关节炎的临床研究OA
Clinical Research on Extracorporeal Shock Wave Acupoint Therapy Combined with Duhuo Jisheng Decoction in the Treatment of Knee Osteoarthritis with Cold-Dampness and Bi-Stagnation Pattern
目的 探讨体外冲击波穴位疗法联合独活寄生汤配合神经肌肉训练治疗寒湿痹阻型膝骨关节炎的临床疗效.方法 选取符合纳入标准的寒湿痹阻型膝骨关节炎患者,依据随机数字表随机分为对照组和观察组,每组各48例.对照组给予神经肌肉训练,观察组在对照组治疗基础上给予体外冲击波穴位疗法联合独活寄生汤治疗,两组均治疗12周;观察两组治疗前后中医证候积分、VAS评分、Lysholm功能评分、膝关节温度、膝关节与上臂内侧温度差,以及血清IL-1β、TNF-α、IL-17含量的变化情况,并比较临床疗效.结果 与治疗前比较,两组治疗后中医证候积分、VAS评分和膝关节温度、膝关节与上臂内侧温度差,以及血清IL-1β、TNF-α、IL-17含量均明显降低(P<0.05),Lysholm评分明显升高(P<0.05),且观察组中医证候积分、VAS评分和膝关节温度、膝关节与上臂内侧温度差、血清IL-1β、TNF-α、IL-17含量低于对照组(P<0.01)、Lysholm评分高于对照组(P<0.01);观察组总有效率为93.75%(45/48),明显高于对照组79.17%(38/48)(P<0.05).结论 体外冲击波穴位疗法联合独活寄生汤配合神经肌肉训练治疗可有效缓解寒湿痹阻型膝骨关节炎患者疼痛症状、改善膝关节功能、减轻炎症反应.
Objective To investigate the clinical efficacy of extracorporeal shock wave acupoint therapy combined with Duhuo Jisheng Decoction and neuromuscular training in the treatment of knee osteoarthritis with cold-dampness and bi-stagnation pattern.Methods Patients of knee osteoarthritis with cold-dampness and bi-stagnation pattern who met the inclusion criteria were selected and randomly divided into a control group and an observation group using the random number table,with 48 cases in each group.The control group received neuromuscular training,while the observation group received extracorporeal shock wave acupoint therapy combined with Duhuo Jisheng Decoction on the basis of the control group's treatment.Both groups were treated for 12 weeks.Changes in traditional Chinese medicine(TCM)syndrome scores,VAS scores,Lysholm functional scores,knee joint temperature,temperature difference between the knee joint and the inner side of the upper arm,as well as serum levels of IL-1β,TNF-α,and IL-17 were observed before and after treatment in both groups,and the clinical efficacy was compared.Results After treatment,both groups showed significant reductions in TCM syndrome scores,VAS scores,knee joint temperature,temperature difference between the knee joint and the inner side of the upper arm,and serum levels of IL-1β,TNF-α,and IL-17(P<0.05),while Lysholm scores significantly increased(P<0.05).Furthermore,the observation group had lower TCM syndrome scores,VAS scores,knee joint temperature,temperature difference between the knee joint and the inner side of the upper arm,and serum levels of IL-1β,TNF-α,and IL-17 than the control group(P<0.01),while Lysholm scores were higher(P<0.01).The total effective rate in the observation group was 93.75%(45/48),significantly higher than 79.17%(38/48)in the control group(P<0.05).Conclusion Extracorporeal shock wave acupoint therapy combined with Duhuo Jisheng Decoction and neuromuscular training can effectively alleviate pain syndrome,improve knee joint function,and reduce inflammatory response in patients of knee osteoarthritis with cold-dampness and bi-stagnation pattern.
王媛媛;朱婷;季晶俊;戎装;李海燕;卞雅莉;潘琦慧
上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021上海中医药大学附属曙光医院,上海 200021
体外冲击波穴位疗法神经肌肉训练独活寄生汤膝骨关节炎
Extracorporeal shock wave acupoint therapyNeuromuscular trainingDuhuo Jisheng DecoctionKnee osteoarthritis
《中医药信息》 2026 (6)
52-57,6
上海市卫生健康委员会科研项目(202240051,20234Y0138)
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