普通外科围手术期肺栓塞预防与管理OA
Prevention and management of perioperative pulmonary embolism in general surgery
普通外科围手术期发生肺栓塞将导致病人死亡风险升高,病人个体及治疗因素、基础疾病、外科医师对出血及血栓栓塞风险的认知均会影响对肺栓塞的诊断评估、预防方案及制定治疗决策.肺栓塞症状、体征、血浆D-二聚体水平、心电图及超声检查缺乏特异性,CT肺动脉造影在血流动力学严重紊乱时无法实施,进而影响诊断准确性.如何优化诊断流程并正确把握抗凝、再灌注治疗的时机,手术前后抗凝药物的暂停、桥接、恢复使用需要规范.介入治疗中导管溶栓、下腔静脉滤器置入的适应证也应当严格把握.
Pulmonary embolism during the perioperative period of general surgery elevates mortality risk.Individual and treatment-related factors,underlying diseases,and the awareness of surgeons to bleeding and thromboembolism risk evaluation may influence the diagnostic assessment,prevention,and treatment strategy of pulmonary embolism.The symptoms,signs,D-dimer levels,electrocardiogram,and ultrasound findings of pulmonary embolism lack specificity.Computed tomography pulmonary angiography(CTPA)may not be feasible in the patients with severe hemodynamic instability,thereby affecting diagnostic accuracy.Therefore,it is essential to optimize the diagnostic protocol,appropriately determine the timing of anticoagulation and reperfusion therapy,and standardize the perioperative management of anticoagulant medications,including discontinuation,bridging,and resumption.Furthermore,indications for interventional treatments such as catheter-directed thrombolysis and inferior vena cava filter placement should be strictly limited.
刘一娜;马晓春
中国医科大学附属第一医院重症医学科,辽宁沈阳 110001中国医科大学附属第一医院重症医学科,辽宁沈阳 110001
医药卫生
围手术期肺栓塞预防抗凝
perioperative periodpulmonary embolismpreventionanticoagulation
《中国实用外科杂志》 2026 (5)
624-628,5
辽宁省教育厅高校基本科研项目(No.LJ232410159031) University Basic Scientific Research Project of Liaoning Provincial Department of Education(No.LJ232410159031)
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