与孤独症谱系障碍相关的小脑结构和功能改变(综述)OACHSSCD

Autism Spectrum Disorder(ASD)is a complex neurodevelopmental disorder.In recent years,the cerebellum-a brain region crucial for social,cognitive,and language functions-has gained increasing attention in ASD research.This review systematically synthesizes recent studies on structural and functional changes in the cere-bellum in ASD,covering multiple dimensions such as morphology,functional connectivity,and microstructural ima-ging.Notably,reductions in gray matter in the cerebellar vermis and posterior lobes(e.g.,crus I/II),as well as dis-rupted connectivity between the cerebellum and frontal/parietal regions,are among the most frequently reported findings.Despite some heterogeneity in cerebellar regions,participant age,and measurement techniques across stud-ies,the cumulative evidence supports the key role of the cerebellum in the development of core symptoms of ASD.