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家畜基因组选种选配技术的研究进展OA

Research progress on breeding and selection techniques for domestic animal genomes

中文摘要英文摘要

随着基因组学技术的快速发展,家畜育种已进入基因组时代.基因组选种选配技术通过整合全基因组标记信息与智能算法,既显著提升了育种选择准确性、缩短世代间隔,又有效平衡了遗传进展与近交控制,从而保障了群体遗传健康,推动实现高效、精准、可持续的现代家畜育种.该文系统综述了基因组选种选配的基本原理与常用模型,包括以GBLUP、ssBLUP为代表的直接法、以贝叶斯法为代表的间接法以及机器学习方法(如支持向量机、随机森林、人工神经网络等),并分析了各模型的适用范围与优缺点.在应用进展方面,基因组选择技术已广泛应用于牛、猪、山羊和绵羊等主要家畜育种中,显著提升了乳用性状、繁殖性能、饲料效率等重要经济性状的遗传进展;基因组选配技术在奶牛、猪等物种中的研究表明,其在协同提升遗传进展、控制近交系数、维持遗传多样性等方面发挥了重要作用.同时,该文还分析了当前该技术面临的数据质量与标准化、计算资源需求、多性状整合、结构变异利用不足以及推广应用中的人才与成本等问题,并对未来研究方向进行了展望.

With the rapid advancement of genomics technologies,livestock breeding has entered the genomic era.Genomic selection and mating techniques,by integrating genome-wide marker information with intelligent algorithms,not only significantly enhance the accuracy of breeding selection and shorten generation intervals,but also effectively balance genetic gain with inbreeding control,thereby safeguarding population genetic health and promoting efficient,precise,and sustainable modern livestock breeding.This article systematically reviews the fundamental principles and common models of genomic selection and mating,including direct methods represented by GBLUP and ssGBLUP,indirect methods such as Bayesian approaches,and machine learning methods(e.g.,support vector machines,random forests,artificial neural networks),while analyzing the applicable scope,advantages,and limitations of each model.Regarding application progress,this article indicates that genomic selection technology has been widely implemented in the breeding of major livestock species such as cattle,pigs,goats,and sheep,significantly enhancing genetic gain for economically important traits including milk production,reproductive performance,and feed efficiency.Studies on genomic mating in dairy cattle and pigs demonstrate its important role in synergistically improving genetic gain,controlling inbreeding coefficients,and maintaining genetic diversity.Furthermore,this article analyzes current challenges facing this technology,including data quality and standardization,computational resource requirements,multi-trait integration,underutilization of structural variations,as well as personnel and cost issues in practical implementation,while providing prospects for future research directions.

刘凤娟;吴铁成;刘俊阳;王涛;意乐其;高玉林;闫新刚;刘斌

鄂尔多斯市立新实业有限公司,内蒙古 鄂尔多斯 017000||内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031鄂尔多斯市立新实业有限公司,内蒙古 鄂尔多斯 017000内蒙古自治区农牧业科学院,内蒙古 呼和浩特 010031

农业科技

基因组选择基因组选配遗传进展基因组育种值近交控制

Genomic selectionGenomic selection matingGenetic progressGenomic breeding valueInbreeding control

《中国畜禽种业》 2026 (5)

70-78,9

鄂尔多斯市重点研发计划项目(YF20250271)2023年度内蒙古引进人才科研启动支持项目.

10.19543/j.cnki.1673-4556.20260330.003

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