体感诱发电位N20对重型颅脑损伤患者短期预后的预测价值OA
Predictive Value of Somatosensory Evoked Potential N20 for Short-term Prognosis of Patients with Severe Craniocerebral Injury
目的:探讨体感诱发电位N20对重型颅脑损伤患者短期预后的预测价值.方法:选取2023年6 月—2025 年 6 月晋城市人民医院收治的重型颅脑损伤患者 103 例,于入院 3 d 进行体感诱发电位 N20监测,并收集患者临床资料,随访 3 个月后参照格拉斯哥预后量表(GOS)评分将患者分为预后良好组(n=70)和预后不良组(n=33),比较两组临床资料、N20 潜伏期、N20 波幅,采用多因素 logistic 回归分析重型颅脑损伤患者短期预后的影响因素,并绘制 ROC 曲线分析 N20 潜伏期、N20 波幅对患者预后的预测价值.结果:预后不良组急性生理与慢性健康评价Ⅱ(APACHEⅡ)评分高于预后良好组(P<0.05);两组性别、年龄、体重指数、合并基础疾病、致伤原因、致伤至入院时间、GCS 评分比较,差异无统计学意义(P>0.05).预后不良组 N20 潜伏期长于预后良好组,N20 波幅短于预后良好组(P<0.05).多因素logistic 回归分析显示,N20 潜伏期、N20 波幅为重型颅脑损伤患者短期预后不良的影响因素(P<0.05).N20 潜伏期、N20 波幅联合检测预测重型颅脑损伤患者短期预后的 AUC 为 0.922,高于各项参数单独检测(P<0.05).结论:体感诱发电位监测 N20 潜伏期、N20 波幅与重型颅脑损伤患者短期预后存在一定关系,且联合应用能提高患者短期预后的预测价值.
Objective:To explore the predictive value of somatosensory evoked potential N20 for the short-term prognosis of patients with severe craniocerebral injury.Method:A total of 103 patients with severe craniocerebral injury admitted to Jincheng People's Hospital from June 2023 to June 2025 were selected.Somatosensory evoked potential N20 monitoring was conducted on the 3rd day after admission,and the clinical data of the patients were collected.After 3 months of follow-up,the patients were divided into the good prognosis group(n=70)and the poor prognosis group(n=33)according to the Glasgow outcome scale(GOS)score.The clinical data,N20 latent phase and N20 amplitude of the two groups were compared.Multivariate logistic regression analysis was used to analyze the influencing factors affecting the short-term prognosis of patients with severe craniocerebral injury.The ROC curve was plotted to analyze the predictive value of N20 latent phase and N20 amplitude for the prognosis of patients.Result:The acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)score of the poor prognosis group was higher than that of the good prognosis group(P<0.05).There were no statistically significant differences in gender,age,body mass index,underlying diseases,causes of injury,time from injury to admission,and GCS score between the two groups(P>0.05).The N20 latent phase in the poor prognosis group was longer than that in the good prognosis group,and the N20 amplitude was shorter than that in the good prognosis group(P<0.05).Multivariate logistic regression analysis showed that N20 latent phase and N20 amplitude were influencing factors for the short-term poor prognosis of patients with severe craniocerebral injury(P<0.05).The AUC of combined detection of N20 latent phase and N20 amplitude in predicting the short-term prognosis of patients with severe craniocerebral injury was 0.922,which was higher than that of individual detection of each parameter(P<0.05).Conclusion:There is a certain relationship between the monitoring of N20 latent phase and N20 amplitude by somatosensory evoked potential and the short-term prognosis of patients with severe craniocerebral injury,and the combined application can improve the predictive value of the short-term prognosis of patients.
申剑波;乔凯鹏
晋城市人民医院神经外科 山西 晋城 048000晋城市人民医院神经外科 山西 晋城 048000
医药卫生
重型颅脑损伤体感诱发电位N20波幅短期预后预测价值
Severe craniocerebral injurySomatosensory evoked potentialN20 amplitudeShort-term prognosisPredictive value
《中国医学创新》 2026 (15)
104-108,5
山西省"四个一批"科技兴医创新计划项目(2022XM24)晋城市科技局项目(20210104)
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