迷走神经磁刺激对脑桥梗死后吞咽障碍患者吞咽功能的影响OA

Objective:To explore the impacts of vagus nerve stimulation(VNS)on swallowing function and serum growth differentiation factor-15(GDF-15),C-reactive protein(CRP),and Visinin like protein-1(VILIP-1)in pa-tients with swallowing disorders after pontine infarction.Methods:From June 2024 to June 2025,80 patients with swallowing disorders after pontine infarction in our hospital were randomly assigned into an electrical stimulation group[using neuromuscular electrical stimulation(NMES)on the basis of routine swallowing rehabilitation train-ing,40 cases]and a magnetic stimulation group(using VNS on top of routine swallowing rehabilitation training,40 cases).The swallowing function,serological indicators,surface electromyography,and quality of life were com-pared.Results:After therapy,the scores of the standard swallowing function assessment scale(SSA)decreased in both groups,and the score of the magnetic stimulation group was prominently lower(P<0.01).After therapy,GDF-15,CRP,and VILIP-1 all decreased in both groups,and the indicators were prominently lower in the magnet-ic stimulation group(P<0.01).After therapy,both groups showed an increase in maximum wave amplitude and a decrease in swallowing duration,with the magnetic stimulation group showing more prominent changes(P<0.01).After therapy,the swallowing-quality of life scale(SWAL-QOL)increased in both groups,and the magnetic stimu-lation group scored prominently higher(P<0.01,0.05).Conclusion:VNS can effectively improve the swallowing function of patients with swallowing disorders after pontine infarction,reduce GDF-15,CRP,and VILIP-1,en-hance pharyngeal surface muscle function,and improve quality of life.