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心脏外科术后急性心肌梗死的临床特征和短期预后OA

Clinical characteristics and short-term prognosis of acute myocardial infarction following cardiac surgery

中文摘要英文摘要

目的 探讨心脏外科术后急性心肌梗死(postoperative acute myocardial infarction,PAMI)患者的临床特征和短期预后.方法 回顾性选择 2015年 2月至 2025年 2月在复旦大学附属中山医院心外科术后行冠状动脉造影的 45例PAMI患者.收集患者一般资料,手术类型,PAMI发病时间、原因,院内恢复情况等.采用单因素 logistic回归模型分析患者院内存活的相关因素.结果 患者年龄(62.40±11.72)岁,31例(68.89%)男性,21例(46.67%)合并高血压.26例(57.78%)患者行心脏瓣膜手术,16例(35.56%)接受冠状动脉旁路移植术.PAMI发病时间为 24(0,48)h,38例(84.44%)患者于术后 48 h内发病.28例(62.22%)患者存在冠脉/桥血管新发病变,20例(44.44%)患者PAMI可能由血栓所致.9例患者院内死亡,13 例不能恢复自动出院,23例恢复后出院.单因素 logistic回归分析显示,冠脉/桥血管新发病变是患者院内存活的危险因素(OR=0.235,P=0.036).结论 心脏外科术后 48 h内容易发生AMI,血栓是导致PAMI的最常见原因.冠脉/桥血管新发病变与短期不良预后相关.

Objective To explore the clinical characteristics and short-term prognosis of postoperative acute myocardial infarction(PAMI)after cardiac surgery.Methods A retrospective study was conducted on 45 PAMI patients who underwent coronary angiography after cardiac surgery at Zhongshan Hospital,Fudan University,from February 2015 to February 2025.General information,type of surgery,onset time and causes of PAMI,and in-hospital recovery condition were collected.Univariate logistic regression was used to analyze factors related to in-hospital survival.Results The patients'age was(62.40±11.72)years,31 cases(68.89%)were male,21 cases(46.67%)had hypertension.Twenty-six patients(57.78%)underwent cardiac valve surgery,and 16 patients(35.56%)received coronary artery bypass grafting.The onset time of PAMI was 24(0,48)hours,with 38 cases(84.44%)developing within 48 hours after surgery.Twenty-eight patients(62.22%)presented with new lesions in coronary arteries/bypass grafts,and 20 patients(44.44%)were considered to have thrombus-induced PAMI.Nine patients died in hospital,13 patients failed to recover and were discharged automatically,and 23 patients were discharged after recovery.Univariate logistic regression analysis showed that new lesion in coronary arteries/bypass grafts was risk factor for in-hospital survival(OR=0.235,P=0.036).Conclusions PAMI frequently occurs within 48 hours post-cardiac surgery,and thrombosis is the most common cause of PAMI.New lesions in coronary arteries/bypass grafts are closely correlated with poor short-term prognosis.

杨婷婷;史昀青;张倍健;钱菊英;常书福;葛均波

复旦大学附属中山医院心导管室,上海 200032复旦大学附属中山医院心外科,上海 200032复旦大学附属中山医院心内科,上海市心血管病研究所,心脏病全国重点实验室,国家卫生健康委缺血性心脏病重点实验室,中国医学科学院病毒性心脏病重点实验室,国家放射与治疗临床医学研究中心,上海 200032复旦大学附属中山医院心内科,上海市心血管病研究所,心脏病全国重点实验室,国家卫生健康委缺血性心脏病重点实验室,中国医学科学院病毒性心脏病重点实验室,国家放射与治疗临床医学研究中心,上海 200032复旦大学附属中山医院心内科,上海市心血管病研究所,心脏病全国重点实验室,国家卫生健康委缺血性心脏病重点实验室,中国医学科学院病毒性心脏病重点实验室,国家放射与治疗临床医学研究中心,上海 200032复旦大学附属中山医院心内科,上海市心血管病研究所,心脏病全国重点实验室,国家卫生健康委缺血性心脏病重点实验室,中国医学科学院病毒性心脏病重点实验室,国家放射与治疗临床医学研究中心,上海 200032

医药卫生

心脏外科手术急性心肌梗死冠脉造影预后

cardiac surgeryacute myocardial infarctioncoronary angiographyprognosis

《中国临床医学》 2026 (3)

486-492,7

上海市科学技术委员会项目(24SF1902300).Supported by Program of Shanghai Municipal Science and Technology Commission(24SF1902300).

10.12025/j.issn.1008-6358.2026.20251250

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