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活体肝脏移植在肝再移植中应用研究进展OA

Progress of living donor liver transplantation in liver re-transplantation

中文摘要英文摘要

在全球供肝资源持续短缺的背景下,活体肝再次移植已成为初次肝移植术后移植物功能衰竭病人的核心补救治疗方式.相较于已故供肝再次移植,活体供肝再移植在供肝可及性、手术并发症及长期生存预后方面具有独特临床优势.胆道并发症、血管栓塞、慢性排斥反应及原发病复发是需行再次肝移植的主要诱因;腹腔严重粘连、复杂血管及胆道重建仍是再次肝移植术中主要技术难点.随着吲哚菁绿分子荧光影像技术、微创技术的应用,活体供肝再移植手术并发症发生率明显减少,远期生存率明显提升.

Against the backdrop of the persistent global shortage of liver graft resources,living-donor liver re-transplantation has become the core salvage treatment modality for patients with graft dysfunction after primary liver transplantation.Compared with deceased-donor liver re-transplantation,it possesses unique clinical advantages in terms of graft accessibility,surgical complications,and long-term survival prognosis.Biliary complications,vascular embolism,chronic rejection,and recurrence of the primary disease are the main inducements requiring re-transplantation;severe intra-abdominal adhesions,complex vascular and biliary reconstruction remain the major technical difficulties during surgery.With the application of ICG molecular fluorescence imaging technology and minimally invasive techniques,surgical complications have been reduced,and the long-term survival rate of patients has been significantly improved.

张文进;张武

浙江中医药大学研究生院,浙江 杭州 310053树兰(杭州)医院肝胆胰外科,浙江 杭州 310022

医药卫生

活体肝移植肝再移植器官捐献活体肝脏再移植

living donor liver transplantationliver re-trans-plantationorgan donationliving liver re-transplantation

《中国实用外科杂志》 2026 (5)

692-696,5

Key Research and Development Project of Zhejiang Province(No.2024C03149) 浙江省重点研发项目(No.2024C03149)

10.19538/j.cjps.issn1005-2208.2026.05.17

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