儿童先天性心脏病诊断相关生物标志物研究进展OA

Congenital heart disease(CHD)is a common congenital defect in children,with a higher incidence in pre-term neonates.Early diagnosis and treatment can effectively alleviate the disease,and significant progress has been made in the diagnosis and management of CHD.However,the current screening system for CHD in China is not yet completely estab-lished,leading to delayed diagnosis in some children and consequently missing the optimal treatment time.All these cause sev-ereimpact on neonatal health.In recent years,with continuous development of biomarker detection,many biomarkers have been applied in clinical diagnosis,treatment,and prognostic assessment.These biomarkers demonstrate advantages such as simplicity,effectiveness,rapidity,and high reproducibility.Herein,research progress on biomarkers for diagnosing CHD in children was reviewed,aiming to clarify the application and development status of biomarkers for diagnosing CHD in children.