基于AHP-CRITIC结合Box-Behnken响应面法优选壮药复方葛花颗粒的提取工艺OA

To optimize the extraction process of Zhuang Medicine Compound Gehua granules based on AHP-CRITIC combined with Box-Behnken response surface methodology.The content of tectoridin,dihydromyricetin and extraction yield in Zhuang Medicine Compound Gehua granules were used as the evaluation indicators.The comprehensive weight coefficients of each indicator were calculated using Analytic Hierarchy Process(AHP)combined with CRITIC method.Taking the water addition ratio,extraction time,and extraction frequency as the examination factors,a multi index comprehensive score combined with Box-Behnken response surface method was used to design experiments and optimize the water extraction process of Zhuang Medicine Compound gehua Granules.The optimal process for the Zhuang Medicine Compound Gehua granules was to selected as adding 12 times of water volume,with extraction time for 1.5 h,and 3 extractions.The extraction process of the Zhuang Medicine Compound Gehua granules determined in this study is stable and feasible,which can provide a reference for the industrial production of Zhuang Medicine Compound Gehua Granules.