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四磨汤治疗胃肠相关疾病研究进展OA

Progress of Research on the Treatment of Gastrointestinal-Related Diseases by Simo Decotion(四磨汤)

中文摘要英文摘要

胃肠道疾病在中医学中归属于脾胃系统疾病范畴,脾胃为气机升降之枢纽,其基本病机为气机升降失调,气机运行失常可致胃肠功能紊乱相关病证.四磨汤源于宋代严用和所著《济生方》,属理气剂,具有行气降逆、宽胸散结之功效,适用于腹胀腹痛、嗳气呃逆、恶心呕吐等病证.回顾数年来相关文献,发现四磨汤在应用于胃肠相关疾病的临床治疗中具有多方面、多靶点的优势.同时分析相关文献发现其分子机制具有抗炎、保护黏膜、促胃肠动力及调节肠道菌群等作用.该文就近年来四磨汤治疗胃肠相关疾病的临床与机制研究进展进行综述,为临床应用提供参考.

Gastrointestinal diseases in Chinese medicine are diseases of the spleen and stomach system,the spleen and stomach is the hub of qi elevation,and its basic pathogenesis is attributed to the disorder of qi movement,which can lead to gastrointestinal disorders.Originating from"Ji Sheng Fang"by Yan Yonghe of the Song Dynasty.Simo Decotion(四磨汤)is a qi-regulating formula,has the effect of qi lowering,broadening the chest to disperse the effect of the knot,applicable to abdominal distension and abdominal pain,erosion,nausea and vomiting and other symptoms.Reviewing the relevant literature over the past few years,it is found that Simo Decotion has multi-faceted and multi-targeted advantages in the clinical treatment of gastrointestinal-related diseases.Meanwhile,analyzing the related literature,we found that its molecular mechanism has the effects of anti-inflammation,protecting mucosa,promoting gastrointestinal dynamics and regulating intestinal flora.The author provides a review of recent clinical and mechanistic studies on the treatment of gas-trointestinal-related diseases with Simo Decotion,aiming to offer a reference for clinical application.

韦佳宋;林才志;梁景菊;吕泓明;谢思鹏;曹育启

广西中医药大学,广西 南宁 530000广西中医药大学第一附属医院,广西 南宁 530023广西中医药大学,广西 南宁 530000广西中医药大学,广西 南宁 530000广西中医药大学,广西 南宁 530000广西中医药大学,广西 南宁 530000

医药卫生

四磨汤临床研究作用机制综述

Simo decotion(四磨汤)clinical researchmechanism of actionreview

《实用中医内科杂志》 2026 (6)

99-102,4

广西自然科学基金资助项目(2024GXNSFAA010240)

10.13729/j.issn.1671-7813.Z25041013

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