厚朴药理作用及临床应用研究进展OA

As a traditional Chinese medicine(TCM)used to dry dampness,resolve phlegm,direct qi downward,and relieve distension,Houpo(Magnoliae Officinalis Cortex)and its herb pairs are widely employed in clinical practice for treating digestive and respiratory diseases.This review focuses on the pharmacological effects of Houpo and its main active constituents.It systematically summarizes modern experimental research findings regarding core clinical herb pairs,including Houpo-Zhishi(Aurantii Fructus Immaturus),Houpo-Zhiqiao(Aurantii Fructus),Houpo-Cangzhu(Atractylodis Rhizoma),Houpo-Banxia(Pinelliae Rhizoma),Houpo-Huanglian(Coptidis Rhizoma),Houpo-Zhizi(Gardeniae Fructus),Houpo-Mahuang(Ephedrae Herba)and Houpo-Yuanzhi(Polygalae Radix).By reviewing recent advances in network pharmacology and clinical applications of Houpo and its herb pairs,this paper aims to elucidate the modern scientific mechanisms underlying its compatibility theories,such as"acrid-opening and bitter-descending"and"drying dampness and invigorating the spleen".The goal is to provide a theoretical basis and research strategies for optimizing compatibility patterns,guiding precise clinical application,and facilitating the development of new TCM drugs.There are 76 references.