首页|期刊导航|吉首大学学报(自然科学版)|面向免疫固定电泳分类的输入增强双尺度网络模型

面向免疫固定电泳分类的输入增强双尺度网络模型OA

Input-Enhanced Dual-Scale Network for Immunofixation Electrophoresis Image Classification

中文摘要英文摘要

针对免疫固定电泳图像存在背景起伏、噪声干扰、条带浅淡而易引发漏检、误判的临床难题,构建了一种 DG-DB-IE2FNet模型.模型中重点设计了动态门控双分支残差块与IFE输入增强双尺度分支.前者用于自适应融合互补卷积分支,后者用于抑制背景并突出条带方向信息.将 ELP,G,A,M,K,L泳道的阴阳性判定设定为多标签预测任务,并基于20 000例真实数据开展多种主流模型的对比实验.结果表明,DGDB-IE2FNet模型在测试集上的准确率达99.63%,阴性预测值达99.74%,灵敏度达98.07%,F1分数达98.56%,整体预测性能优于其他对比模型.

To address the clinical challenges of immunofixation electrophoresis images,such as background fluctuations,noise interference,and faint bands leading to missed detections and misdiagnoses,we pro-pose a DGDB-IE2FNet model.The model features a dynamically gated dual-branch residual block and an IFE input enhancement dual-scale branch.The former adaptively fuses complementary convolutional branches,while the latter suppresses background noise and enhances directional information of bands.We formulate the classification of positive/negative results for ELP,G,A,M,K,and L lanes as a multi-label prediction task and conduct comparative experiments with several mainstream models using 20 000 real-world cases.Results show that the DGDB-IE2FNet achieves an accuracy of 99.63%,negative predictive value of 99.74%,sensitivity of 98.07%,and F1 score of 98.56%on the test set,outperforming other compared models in overall prediction performance.

符笑添;谢剑宇;谭子涵;李曙

吉首大学通信与电子工程学院,湖南 吉首 416000吉首大学通信与电子工程学院,湖南 吉首 416000吉首大学通信与电子工程学院,湖南 吉首 416000广州医科大学生物医学工程学院,广东 广州 511000

信息技术与安全科学

免疫固定电泳深度学习卷积神经网络双尺度

immunofixation electrophoresisdeep learningconvolutional neural networksdual-scale

《吉首大学学报(自然科学版)》 2026 (3)

41-49,9

10.13438/j.cnki.jdzk.2026.03.007

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