首页|期刊导航|辽宁中医杂志|感染后咳嗽患者接受宣肺止嗽合剂治疗的依从性及安全性观察

感染后咳嗽患者接受宣肺止嗽合剂治疗的依从性及安全性观察OA

Evaluation on Compliance and Therapeutic Safety of Xuanfei Zhisou Mixture(宣肺止嗽合剂)Therapy in Post-infectious Cough Patients

中文摘要英文摘要

目的 考察风邪犯肺型感染后咳嗽患者服用宣肺止嗽合剂的依从性和安全性.方法 研究共收治240例患者,随机分为对照组(口服宣肺止嗽合剂模拟剂)和试验组(口服宣肺止嗽合剂),120例/组,7 d为1个疗程.采用安全性(safety set,SS)集对两组的用药依从性、安全性指标进行比较.结果 所有患者均进入SS集进行分析.对照组用药依从性好的患者占比为76.47%(91/120),试验组占比为79.66%(94/120),两组占比相近(P>0.05).对照组3例患者出现不良事件5例次,试验组2例患者出现不良事件2例次,组间相近(P>0.05).结论 风邪犯肺型感染后咳嗽患者采用宣肺止嗽合剂治疗的用药依从性和安全性较高,值得临床推广.

Objective To assess the treatment adherence and therapeutic safety of Xuanfei Zhisou Mixture(宣肺止嗽合剂)in the patients suffering from post-infectious cough(wind evil invading lung).Methods A total of 240 patients were randomly divid-ed into control group(treated with Xuanfei Zhisou Mixture simulation agent)and trial group(treated with Xuanfei Zhisou Mix-ture),with 120 cases in each group,both were treated for seven days.Safety set(SS)was used to evaluate the treatment adherence and safety.Results All patients entered the SS for analysis.The proportion of the patients in control group with good treatment ad-herence was 76.47%(91/120),79.66%(94/120)in trial group,and the proportion was similar(P>0.05).In control group,there were five adverse events occurred in four subjects,while in trial group,there were two adverse events occurred in two sub-jects,the occurrence rate was similar(P>0.05).Conclusion Xuanfei Zhisou Mixture had high compliance and therapeutic safe-ty,and is worthy of widely use for post-infectious cough(wind evil invading lung).

崔红生;张洪春;杨道文;高峰;封继宏;朱佳;吕红霞;陈双明

北京中医药大学第三附属医院,北京 100029中日友好医院,北京 100029中日友好医院,北京 100029中国中医科学院望京医院,北京 100102天津中医药大学第二附属医院,天津 300150江苏省中医院,江苏南京 210004北京康义堂中医研究院,北京 100070||北京康众时代医学研究发展有限公司,北京 100073甘肃普安制药股份有限公司,甘肃武威 733006

医药卫生

感染后咳嗽宣肺止嗽合剂依从性安全性

post-infectious coughXuanfei Zhisou Mixture(宣肺止嗽合剂)treatment adherencetherapeutic safety

《辽宁中医杂志》 2026 (6)

86-88,3

甘肃省科技计划项目(22ZD6FA021-2)

10.13192/j.issn.1000-1719.2026.06.023

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