中医药在治疗伴有高雄症状的多囊卵巢综合征中的应用研究OA
Research on the Application of Traditional Chinese Medicine in the Treatment of Polycystic Ovary Syndrome with Hyperandrogenic Symptoms
多囊卵巢综合征(PCOS)是一种以高雄症状(包括高雄激素血症、多毛、痤疮等)、月经异常和排卵障碍为主要特征的内分泌代谢紊乱性疾病,严重影响患者生殖健康与生活质量.高雄症状作为 PCOS 病理生理进程的关键驱动因素,是临床干预的核心靶点.中医药基于"辨证施治"理论,通过经典方剂(如苍附导痰汤、半夏泻心汤、知柏地黄汤、丹栀逍遥散等)及中成药(如桂枝茯苓丸、坤泰胶囊、定坤丹)多途径调控雄激素水平,在改善多毛、痤疮等外在症状的同时,兼具改善胰岛素抵抗、调节卵巢功能等作用.该文系统综述了中医药在 PCOS 高雄症状治疗中的应用现状、作用机制、临床前景及不足,以期为 PCOS 的中西医结合治疗提供理论依据和研究方向,推动中医药在该领域的规范化应用.
Polycystic ovary syndrome(PCOS)is an endocrine and metabolic disorder characterized by hyperan-drogenemia(including hyperandrogenemia,hirsutism,acne,etc.),menstrual abnormalities,and ovulation disorders,severely impacting patients'reproductive health and quality of life.Hyperandrogenemia,as a key driver of the patho-physiological process of PCOS,is a core target for clinical intervention.Traditional Chinese medicine(TCM),based on the theory of"syndrome differentiation and treatment,"regulates androgen levels through multiple pathways using classic formulas(such as Cangfu Daotan Decoction,Banxia Xiexin Decoction,Zhibai Dihuang Decoction,and Danzhi Xiaoyao Powder)and prepared Chinese medicines(such as Guizhi Fuling Pill,Kuntai Capsule,and Dingkun Pill).This not only improves external symptoms such as hirsutism and acne but also improves insulin resistance and regulates ovarian function.This article systematically reviews the current application,mechanism of action,clinical prospects,and limitations of TCM in the treatment of hyperandrogenemia in PCOS,aiming to provide theoretical basis and re-search directions for the integrated TCM and Western medicine treatment of PCOS and promote the standardized appli-cation of TCM in this field.
王絮;柳奕灿;孙云
浙江中医药大学附属温州市中医院 浙江 温州 325000浙江中医药大学附属温州市中医院 浙江 温州 325000浙江中医药大学附属温州市中医院 浙江 温州 325000
医药卫生
多囊卵巢综合征高雄症状方剂中医药
Polycystic ovary syndromeHyperandrogenic symptomsFormulaTraditional Chinese medicine
《中医药临床杂志》 2026 (5)
1070-1075,6
浙江省温州市科技计划项目(ZY2022014)浙江中医药大学科研项目资助(2022FSYYZY27)
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