Nontyphoidal Salmonella encephalopathy in a teenager from Hubei,ChinaOA
Nontyphoidal Salmonella(NTS)encephalopathy is rare,especially without gastroenteritis.We report a case in a healthy 14-year-old girl presenting with rash and headache,but no diarrhea.Cerebrospinal fluid culture grew Gram-negative bacilli.Genomic sequencing identified a multidrug-resistant Salmonella Typhimurium ST36 strain.The patient progressed to subarachnoid hemorrhage.This case highlights that invasive NTS disease can present atypically in adolescents.NTS should be considered in encephalopathy differentials,irrespective of intestinal symptoms.
Hui-Ju Han;Ya-Ting Zhang;Jun-Jing Yang;Wen-Jie Wang;Jian-Bo Zhan
School of Public Health,Shandong First Medical University(Shandong Academy of Medical Sciences),Jinan 271016,Shandong Province,ChinaHubei Provincial Center for Disease Control and Prevention,Wuhan 430079,Hubei Province,ChinaHubei Provincial Center for Disease Control and Prevention,Wuhan 430079,Hubei Province,ChinaSchool of Public Health,Shandong First Medical University(Shandong Academy of Medical Sciences),Jinan 271016,Shandong Province,ChinaHubei Provincial Center for Disease Control and Prevention,Wuhan 430079,Hubei Province,China
医药卫生
SalmonellaEncephalopathyChildGenome
《Infectious Medicine》 2026 (1)
P.74-77,4
supported by the Shandong Provincial Natural Science Foundation(Grant Number:ZR2023QH318).
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