ERAS理念下行个体化肠内营养对结直肠癌患者免疫功能和炎症因子水平的影响OA
Impact of individualized enteral nutrition under the ERAS concept on the immune function and inflammatory factor levels in patients with colorectal cancer
目的 分析快速康复外科(ERAS)理念下行个体化肠内营养对结直肠癌患者免疫功能和炎症因子水平的影响.方法 选择随机数字表法将福建医科大学附属南平第一医院 2023 年3 月至2025 年7 月收治的96 例结直肠癌患者分为研究组(48 例,ERAS理念下个体化肠内营养)及对照组(48 例,常规管理).比较 2 组围手术期恢复指标、免疫功能、炎症因子、营养指标及并发症.结果 研究组的首次排气、排便时间均早于对照组,住院时间短于对照组(P均<0.05).术后 1 d及 3 d,研究组的炎症因子及营养指标均较对照组更优(P均<0.05).研究组的并发症发生率较对照组低(P<0.05).结论 ERAS理念下行个体化肠内营养能促进结肠癌患者术后胃肠道功能恢复,减少免疫功能及炎症因子波动.
Objective To analyze the effects of individualized enteral nutrition under the concept of enhanced recovery after surgery(ERAS)on immune function and inflammatory factor levels in patients with colorectal cancer.Methods A total of 96 patients with colorectal cancer admitted to Nanping First Hospital Affiliated to Fujian Medical University from March 2023 to July 2025 were divided into a study group of 48 cases(individualized enteral nutrition under the ERAS concept)and a control group of 48 cases(conventional management)using a random number table method.Perioperative recovery indicators,immune function,inflammatory factors,nutritional indicators,and complications were compared between the two groups.Results The first exhaust and defecation time,as well as the hospitalization time in the study group were earlier or shorter than those in the control group(P<0.05).At postoperative day 1 and day 3,the inflammatory factors and nutritional indicators in the study group were superior to those in the control group(P<0.05).The incidence of complications in the study group was lower than that in the control group(P<0.05).Conclusion Individualized enteral nutrition under the ERAS concept can promote the recovery of gastrointestinal function in patients with colorectal cancer after surgery and reduce fluctuations in immune function and inflammatory factors.
魏瑶;张文
福建医科大学附属南平第一医院,福建 南平,353000南平市延平区大横镇卫生院,福建 南平,353000
医药卫生
结直肠癌快速康复外科肠内营养免疫功能炎症因子
colorectal cancerenhanced recovery after surgeryenteral nutritionimmune functioninflammatory factor
《中西医结合护理(中英文)》 2026 (1)
9-12,4
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