基于肠道微生态特征的脑卒中患者肠内营养支持策略构建及应用OA

Objective To construct enteral nutrition support strategy for stroke patients based on gut microbiota characteristics,and to explore its application value.Methods Ninety cases of stroke patients admitted to the Affiliated Hospital of Xuzhou Medical University from February 2022 to February 2024 were divided into an observation group(n=45)and a control group(n=45)by a simple random sampling method.Both groups received routine care,while the observation group was additionally given enteral nutrition support based on the characteristics of gut microbiota.The nutritional status,gastrointestinal function,self-care ability and neurological function of the two groups were compared before and after the intervention,and the recovery conditions and occurrence of complications of the two groups were compared.Results After 7 days of intervention,the levels of serum albumin(ALB),prealbumin(PA),total protein(TP),gastrin(GAS)and motilin(MOT)in the observation group were higher than those in the control group(P<0.05).After 7 days of intervention,the Barthel index(BI)of the observation group was higher than that of the control group,and the National Institutes of Health Stroke Scale(NIHSS)score of the observation group was lower than that of the control group(P<0.05).The recovery time of drinking water and oral intake in the observation group was earlier than that in the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion The enteral nutrition support strategy based on gut microbiota characteristics can help stroke patients improve their nutritional status,gastrointestinal function,promote the recovery of self-care ability and neurological function,and help shorten the recovery time and reduce the incidence of complications.