枸杞多糖的提取、分离纯化及药理作用OA

Lycium barbarum is a medicinal and edible traditional Chinese medicine,with Lycium barbarum polysaccharides as its main active components.Modern research has confirmed its multiple pharmacological effects.Extraction methods for Lycium barbarum polysaccharides included hot water extraction,enzymatic hydrolysis,ultrasonic-assisted extraction,and supercritical fluid extraction technology.The extraction yield varied significantly depending on the extraction method,among which microwave-assisted composite enzyme extraction yields the highest.Separation and purification were primarily achieved through chromatography,solvent precipitation,and membrane separation techniques.The monosaccharide composition was predominantly composed of rhamnose,arabinose,and galactose,with variations in monosaccharide components across different purification processes.Lycium barbarum polysaccharides exhibit broad pharmacological effects,including antitumor activity,vision protection,antibacterial properties,hepatorenal function protection,and reproductive system support.Molecular mechanisms underlying some pharmacological effects have also been extensively studied.However,current research on Lycium barbarum polysaccharides still faces challenges such as low extraction yields,complex purification processes,and inconsistent quality standards.This review can provide references for further development and research on Lycium barbarum polysaccharides.