前庭性偏头痛患者抑郁情绪现状调查及其与前庭功能的关系OA
Investigation on the Current Status of Depressive Mood in Patients with Vestibular Migraine and Its Relationship with Vestibular Function
目的 探讨前庭性偏头痛(VM)患者抑郁情绪状况及其与前庭功能的关系.方法 回顾性收集2023年12月至2025年9月在武汉市中西医结合医院诊治的101例VM患者的临床资料.采用汉密尔顿抑郁量表(HAMD)调查患者抑郁情绪状况,并将101例患者分为抑郁组(48例,HAMD评分≥7分)和非抑郁组(53例,HAMD评分<7分).评估患者前庭功能,分析患者抑郁情绪与前庭功能的关系.结果 101例VM患者HAMD得分平均为(7.70±2.10)分.抑郁组摇头试验异常、冷热试验异常、颈肌性前庭诱发电位检查(cVEMP)异常、最大慢相速度、半规管轻瘫值、cVEMP双侧不对称比、病程≥4周、眩晕障碍量表评分≥60分比例均高于非抑郁组(P<0.05).Spearman相关性分析显示,VM患者最大慢相速度、半规管轻瘫值、cVEMP双侧不对称比与HAMD评分均呈正相关(P<0.05).二元Logistic回归分析显示,摇头试验异常、冷热试验异常、cVEMP异常及眩晕障碍量表评分≥60分均为VM患者抑郁情绪的独立影响因素(P<0.05).结论 在VM患者中抑郁情绪较为常见,且与摇头试验异常、冷热试验异常、cVEMP异常等前庭功能异常关系密切,临床应重视对VM患者进行抑郁筛查及前庭功能评估,以实施综合管理.
Objective To investigate the depression status and its relationship with vestibular function in patients with vestibular migraine(VM).Methods Clinical data of 101 patients with VM diagnosed and treated in Wuhan Hospital of Integrated Traditional Chinese and Western Medicine from December 2023 to September 2025 were retrospectively collected.The Hamilton Depression Rating Scale(HAMD)was used to investigate the patients'depression status,and 101 patients were divided into depression group(n=48,HAMD score≥7 points)and non-depression group(n=53,HAMD score<7 points).The vestibular function of patients was evaluated,and the relationship between depression and vestibular function was analyzed.Results The average HAMD score of 101 patients with VM was(7.70±2.10)points.The proportions of abnormal head-shaking test,abnormal caloric test,abnormal cervical vestibular evoked myogenic potential(cVEMP)examination,elevated maximum slow phase velocity,elevated canal paresis value,elevated cVEMP bilateral asymmetry ratio,disease course≥4 weeks and Dizziness Handicap Inventory(DHI)score≥60 points in the depression group were all higher than those in the non-depression group(P<0.05).Spearman correlation analysis showed that the maximum slow phase velocity,canal paresis value and cVEMP bilateral asymmetry ratio were positively correlated with HAMD score in patients with VM(P<0.05).Binary logistic regression analysis showed that abnormal head-shaking test,abnormal caloric test,abnormal cVEMP and DHI score≥60 points were independent influencing factors of depression in patients with VM(P<0.05).Conclusion Depression is relatively common in patients with VM,and it is closely associated with vestibular dysfunction such as abnormal head-shaking test,abnormal caloric test and abnormal cVEMP.Clinically,simultaneous depression screening and vestibular function assessment should be emphasized for patients with VM to carry out comprehensive management.
肖瑶;龙媛熙;杨兴;邱玲;吕晓强;张礼梅;朱俊宇
武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033武汉市中西医结合医院神经内科,武汉 430033
前庭性偏头痛抑郁前庭功能危险因素
vestibular migrainedepressionvestibular functionrisk factors
《转化医学杂志》 2026 (6)
906-911,6
湖北省自然科学基金计划项目(2025AFC109)
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