急性结石性胆囊炎患者的中医证候分布特征及临床指标分析OA
Analysis of traditional Chinese medicine syndrome distribution characteristics and clinical indicators in patients with acute calculous cholecystitis
目的:研究急性结石性胆囊炎患者的中医证候分布特点,并总结不同证候与临床炎症指标的关系.方法:回顾性收集2024年1月-2025年12月天津市中西医结合医院收治的109例急性结石性胆囊炎患者的临床资料,根据中医四诊信息结合疾病特点,将其分为热毒炽盛证12例,胆腑郁热证97例.比较不同证型患者的一般资料、总住院时间、术后住院时间、入院体温、白细胞计数、中性粒细胞比例、C-反应蛋白、胆囊壁厚度、胆囊长径、术后胆漏、腹泻及腹胀等指标的差异.结果:热毒炽盛证患者在年龄、合并糖尿病、总住院时间及术后住院时间、入院体温、白细胞计数、中性粒细胞比例、C-反应蛋白等指标上与胆腑郁热证患者差异均有统计学意义(P<0.05).结论:热毒炽盛证急性结石性胆囊炎患者虽占比较少,但病情最重.中医证型与炎症指标、胆囊超声形态学特征存在相关性,为临床精准评估病情、指导治疗决策提供依据.
Objective To observe the distribution characteristics of Traditional Chinese Medicine(TCM)syndrome patterns in patients with acute calculous cholecystitis and to summarize the corresponding relationships between different syndromes and inflammatory indicators as well as ultrasonographic morphology.Methods A retrospective analysis was conducted on 109 patients with acute calculous cholecystitis treated at Tianjin Hospital of Integrated Traditional Chinese and Western Medicine from January 2024 to December 2025.Based on TCM four-diagnosis information and disease characteristics,the patients were classified into two main syndrome types:heat-toxin exuberance syndrome(n=12)and gallbladder fu depression-heat syndrome(n=97).Descriptive statistical methods were used to analyze the distribution features of each syndrome type,and differences between the groups in basic clinical data,total hospital stay,postoperative hospital stay,admission body temperature,white blood cell count(WBC),neutrophil percentage,C-reactive protein(CRP),gallbladder wall thickness,and gallbladder length were compared.Results Significant differences were found between patients with heat-toxin exuberance syndrome and those with gallbladder fu depression-heat syndrome in terms of age,comorbid diabetes,total hospital stay,postoperative hospital stay,admission body temperature,WBC,neutrophil percentage,and CRP levels(P<0.05).Conclusion Although the heat-toxin exuberance syndrome accounts for a smaller proportion,it is associated with the most severe condition.TCM syndrome types show correlations with inflammatory indicators and ultrasonographic morphological changes of the gallbladder,providing a basis for precise clinical assessment and guiding treatment decisions.
崔志刚;郑欣;孙阳;魏明
天津市中西医结合医院 急诊医学科(天津 300100)天津市中西医结合医院 急诊医学科(天津 300100)天津市中西医结合医院 急诊医学科(天津 300100)天津市中西医结合医院 妇产科(天津 300100)
医药卫生
急性结石性胆囊炎中医证候炎症指标
Acute calculous cholecystitistraditional Chinese medicine syndromeinflammatory indicators
《中国中西医结合外科杂志》 2026 (3)
347-349,3
天津市卫生健康科技项目资助(TJWJ2024MS042)河北省中医药管理局科研计划项目(T2025038)天津市教委科研计划项目(2024KJ247)
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