心房颤动脉冲电场消融术后复发的机制和对策OA
Mechanisms and countermeasures of recurrence of atrial fibrillation after pulsed field ablation
脉冲电场消融(PFA)作为一种新型非热能消融技术,凭借其组织选择性强、安全性高等优势,在心房颤动(房颤)导管消融治疗中展现出广阔的前景.然而,现有文献表明,PFA并未显著提升阵发性房颤的手术疗效;在持续性房颤治疗中,虽有报道PFA成功率较射频消融时代有所提高,但仍缺乏随机对照研究证据.因此,PFA术后复发问题依然值得密切关注.深入理解其复发机制并采取针对性防治对策,对于进一步提升PFA治疗房颤的长期成功率具有重要意义.
As a novel non-thermal ablation technique,pulsed field ablation(PFA)has demonstrated broad prospects in catheter ablation for atrial fibrillation(AF)due to its advantages of strong tissue selectivity and high safety.However,according to the literature currently published,PFA has not improved the surgical efficacy in paroxysmal AF.In the treatment of persistent AF,although relevant reports suggest that the success rate of PFA is higher than in the era of radiofrequency ablation,there is still a lack of evidence from randomized controlled trials(RCTs).Thus,the issue of postoperative recurrence remains a matter of close concern.In-depth understanding of the mechanisms underlying recurrence after PFA and the implementation of targeted prevention and treatment strategies are of great significance for further enhancing the long-term success rate of PFA in AF treatment.
辛小宇;李新忠;王月刚
南方医科大学南方医院心血管内科,广东 广州 510515南方医科大学南方医院心血管内科,广东 广州 510515南方医科大学南方医院心血管内科,广东 广州 510515
医药卫生
心房颤动脉冲电场消融复发对策
atrial fibrillationpulse field ablationrecurrencestrategies
《中国实用内科杂志》 2026 (5)
373-377,5
广东省自然科学基金(2023A1515011833,2026A1515012564)
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