ResNet-152在脑胶质瘤MRI诊断中的应用研究OA
The application of ResNet-152 on diagnosis of glioma based on MRI
目的:本研究采用人工神经网络对胶质瘤患者的脑部MRI图像进行学习,旨在建立胶质瘤的辅助诊断模型.方法:本研究纳入我院 241 例胶质瘤患者,共获得 4 456 张T1WI图像和 4 451 张T2WI图像.对于T1WI和T2WI图像,我们分别按照 7∶3 的比例将图像数据分为训练集和测试集.使用ResNet-152 建立分类模型.使用准确率、阳性预测值(PPV)、灵敏度、特异度、阴性预测值(NPV)、ROC曲线下的面积(AUC)和F1 值来评估ResNet-152 模型的分类效果.结果:T1WI模型的准确率为 88.40%,PPV为 89.71%,敏感性为 82.34%,特异性为 92.93%,NPV为 87.55%,F1 值为 91.29%.ROC曲线的AUC为 0.886.T2WI模型的准确率为 93.55%,PPV为 95.27%,敏感性为 89.42%,特异性为 96.52%,NPV为 92.09%,F1 值为 92.25%.ROC曲线的AUC为0.930.结论:ResNet-152 网络在将MRI图像分类为胶质瘤MRI和正常MRI方面表现良好.ResNet-152 模型在T2WI序列上的综合分类效率高于T1WI.
Objective:This study used artificial neural network to learn the cerebral MRI images of glioma patients to es-tablish auxiliary diagnosis model of glioma.Methods:A total of 241 patients from Tianjin Huanhu Hospital were included in-to this study.For them,there were 4 456 T1WI images and 4 451 T2WI images.For T1WI and T2WI images,we devided thd image data into train set and test set according to the ratio of 7∶3.ResNet-152 was used to establish the classification model.Accuracy,positive predic-tive value(PPV),sensitivity,specificity,negative predictive value(NPV),the area under the curve(AUC)of ROC and F1-measure were used to evaluate the classification effect of the ResNet-152 model.Results:For T1WI,the accuracy of the model was 88.40%,the PPV was 89.71%,the sensitivity was 82.34%,the specificity was 92.93%,the NPV was 87.55%,and the F1-measure was 91.29%.The AUC of ROC curve was 0.886.For T2WI,the accuracy of the model was 93.55%,the PPV was 95.27%,the sensitivity was 89.42%,the speci-ficity was 96.52%,the NPV was 92.09%,and the F1-measure was 92.25%.The AUC of ROC curve was 0.930.Conclusion:The ResNet-152 network performs well in classifying the MRI images into glioma and normal.The classification efficiency of ResNet-152 model on T2WI sequence is higher than that on T1WI sequence.
井奚月;冯全志;张晓晨;韩彤
天津市环湖医院 天津市脑血管与神经变性重点实验室,天津 300222天津市环湖医院 天津市脑血管与神经变性重点实验室,天津 300222天津市环湖医院 天津市脑血管与神经变性重点实验室,天津 300222天津市环湖医院 天津市脑血管与神经变性重点实验室,天津 300222
医药卫生
神经胶质瘤磁共振成像
GliomaMagnetic Resonance Imaging
《中国临床医学影像杂志》 2026 (5)
305-308,4
天津市卫生健康科技项目资助(编号TJWJ2022QN062).
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