低剂量不同分布形态骨水泥治疗骨质疏松性椎体压缩骨折的临床疗效分析OA

Objective To investigate the difference in clinical efficacy between different distribution patterns of low-dose bone cement in percutaneous vertebroplasty(PVP)for the treatment of osteoporotic vertebral compression fractures(OVCFs).Methods A retrospective analysis was conducted on 80 patients with OVCFs treated between March 2022 and March 2024.Based on postoperative imaging evaluation of bone cement distribution,patients were divided into a fused pattern group(fused group,n=40)and a separated pattern group(separated group,n=40).All cases received a single-level injection of 2 to 3 mL of bone cement.The fused group included 14 males and 26 females,aged 60 to 88 years with a mean of(75.4±4.8)years,with a cement volume of 2.0 to 3.0 mL(2.65±0.18)mL.The separated group included 15 males and 25 females,aged 60 to 86 years with a mean fo(75.3±4.8)years,with a cement volume of 2.0 to 3.0 mL(2.63±0.20)mL.Operative time,number of fluoro-scopic exposures,and blood loss were recorded.The anterior height ratio and anterior-posterior height ratio of the injured verte-bra,as well as the sagittal Cobb angle,were measured preoperatively and at 3 months and 1 year postoperatively.Functional disability was assessed using the Oswestry disability index(ODI),and pain was evaluated using the visual analogue scale(VAS).Results All patients were followed up for at least one year.There were no significant differences between the two groups regarding operative time,fluoroscopic exposures,or blood loss(P＞0.05).Preoperative anterior height ratio,anterior-pos-terior height ratio,and Cobb angle were comparable between the groups(P＞0.05).At 3 months and 1 year postoperatively,both groups showed significantly increased height ratios and decreased Cobb angles compared to preoperative values(P＜0.05).However,at these time points,the separated group exhibited significantly higher anterior and anterior-posterior height ratios and a smaller Cobb angle compared to the fused group(P＜0.05).Both groups showed significant improvements in VAS and O-DI scores at 3 months and 1 year compared to preoperative levels(P＜0.001).Notably,the separated group demonstrated sig-nificantly lower VAS and ODI scores than the fused group at both 3 months and 1 year(P＜0.05).Furthermore,the incidence of adjacent vertebral fractures was significantly higher in the fused group than in the separated group(P＜0.05).Conclusion In OVCF patients treated with low-dose(2 to 3 mL)PVP,a separated bone cement distribution pattern yields superior clinical outcomes.It provides better restoration and maintenance of vertebral height and alignment,more effective pain relief,improved functional recovery,and a lower risk of adjacent vertebral fractures compared to a fused pattern.This technique holds signifi-cant clinical value.