首页|期刊导航|中国骨伤|使用自制植骨器椎体内自体骨联合骨诱导材料植骨治疗胸腰椎爆裂骨折

使用自制植骨器椎体内自体骨联合骨诱导材料植骨治疗胸腰椎爆裂骨折OA

Treatment of thoracolumbar burst fractures using a self-designed device for intracorporeal autografting combined with osteoinductive materials

中文摘要英文摘要

目的:探讨自制植骨器经椎弓根椎体内自体骨联合骨诱导材料植骨在治疗胸腰椎骨折中的意义及其疗效.方法:回顾性分析2016年5月至2020年3月诊断为单节段胸腰椎爆裂骨折的40例患者的临床资料,按手术方式分组,其中20例行常规手术单纯切开复位椎弓根钉内固定为常规手术组,男12例,女8例,年龄(41.71±8.25)岁;另20例使用自制植骨器经椎弓根椎体内自体骨联合骨诱导材料植骨配合椎弓根钉内固定为自制植骨器组,男15例,女5例,年龄(40.09±7.59)岁.术前及术后随访时行X线和CT检查,测量伤椎椎体压缩率、后凸畸形角度Cobb角及矫正角度.采用视觉模拟评分(visual analogue scale,VAS)、改良Oswestry功能障碍指数(Oswestry disability index,ODI)评价临床疗效.结果:两组患者均获得随访,时间12~24(15.51±4.98)个月.两组术后2~3周佩戴支具下地活动,无感染、内固定失效、神经损伤加重等不良并发症.两组脊柱Cobb角术后较术前均改善,差异有统计学意义(P<0.05);末次随访自制植骨器组Cobb角(4.1±2.9)°,小于常规手术组(8.2±9.6)°,差异有统计学意义(P<0.05);自制植骨器组矫正度数丢失(1.8±1.5)°,小于常规手术组(7.6±8.4)°,差异有统计学意义(P<0.05).两组椎体高度降低术后较术前均明显改善,差异有统计学意义(P<0.05);末次随访自制植骨器组椎体高度降低(7.4.±1.5)%,小于常规手术组(12.8±6.0)%,差异有统计学意义(P<0.05);自制植骨器组矫正高度丢失(1.6±0.7)%,小于常规手术组(7.9±5.4)%,差异有统计学意义(P<0.05).两组末次随访VAS、ODI均较术前明显降低,差异均有统计学意义(P<0.05).试验组中CT复查,所有植骨已被自体骨替代.结论:使用自制椎体内植骨器治疗胸腰椎新鲜爆裂骨折,术中经伤椎椎弓根进行椎体内自体骨混合骨诱导材料混合植骨联合椎弓根钉内固定,可恢复伤椎椎体高度,重建前、中柱的稳定性,能有效恢复椎体高度和防止术后矫正度丢失并保留脊柱活动度,临床效果满意.

Objective To investigate the clinical significance and efficacy of using a self-designed bone graft device for transpedicular intracorporeal autografting combined with osteoinductive materials in the treatment of thoracolumbar fractures.Methods A retrospective analysis was conducted on 40 patients diagnosed with single-level thoracolumbar burst fractures be-tween May 2016 and March 2020.Patients were divided into two groups based on surgical technique:the conventional surgery group(n=20)underwent open reduction and pedicle screw fixation alone,including 12 males and 8 females with an age of(41.71±8.25)years old;the self-designed device group(n=20)received additional intracorporeal autografting combined with osteoinductive materials using the self-designed device,including 15 males and 5 females with an age of(40.09±7.59)years old.Preoperative and postoperative follow-up assessments included X-ray and CT scans to measure vertebral compression rate,kyphosis angle(Cobb angle),and correction loss.Clinical outcomes were evaluated using the visual analogue scale(VAS)and Oswestry disability index(ODI).Results All patients were followed up,and the duration ranged from 12 to 24 months with a mean of(15.51±4.98)months.Both groups began ambulation with brace protection at 2 to 3 weeks postoperatively,with no complications such as infection,implant failure,or neurological deterioration.Postoperative Cobb angles improved significantly in both groups(P<0.05).At the final follow-up,the Cobb angle in the self-designed device group was(4.1±2.9)°,significantly lower than that in the conventional surgery group(8.2±9.6)°,with a statistically significant difference(P<0.05).The correc-tion degree loss in the self-designed device group was(1.8±1.5)°,significantly lower than that in the conventional surgery group(7.6±8.4)°,with a statistically significant difference(P<0.05).Vertebral height restoration was significantly improved in both groups postoperatively(P<0.05).At the final follow-up,the vertebral height reduction in the self-designed device group was(7.4±1.5)%,significantly lower than that in the conventional surgery group(12.8±6.0)%,with a statistically significant difference(P<0.05).The loss of corrective height in the self-designed device group was(1.6±0.7)%,also significantly lower than that in the conventional surgery group(7.9±5.4)%,with a statistically significant difference(P<0.05).Both groups showed significant reductions in VAS and ODI scores at final follow-up(P<0.05).CT scans in the self-designed device group confirmed complete incorporation of all grafts.Conclusion The use of a self-designed intracorporeal bone graft device for transpedicular autografting combined with osteoinductive materials and pedicle screw fixation effectively restores vertebral height,reconstructs anterior and middle column stability,prevents postoperative correction loss,and preserves spinal mobility in patients with fresh thoracolumbar burst fractures,yielding satisfactory clinical outcomes.

崔志栋;张大鹏

濮阳油田总医院,河南 濮阳 457000濮阳油田总医院,河南 濮阳 457000

医药卫生

胸椎腰椎脊柱骨折骨移植骨折固定术,内

Thorax vertebraeLumbar vertebraeSpinal fracturesBone transplantationFracture fixation,internal

《中国骨伤》 2026 (5)

473-480,8

濮阳市社会发展领域科技攻关计划项目(编号:2503024)Puyang City Social Development Field Science and Technology Attack Plan Project(No.2503024)

10.12200/j.issn.1003-0034.20250146

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