The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expressionOA
The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expression
Xin Zhang;Zhenglai Ma;Tong Zhang;Hao Wu;Bin Su;Qianqian Xu;Junyan Jin;Hongxia Yan;Xiaofan Lu;Zhen Li;Zhiying Liu;Rui Wang;Lin Yuan
Beijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China||Central Laboratory,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China||The Scientific and Technological Achievement Transformation Center,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,ChinaBeijing Key Laboratory for HIV/AIDS Research,Sino-French Joint Laboratory for HIV/AIDS Research,Clinical and Research Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China
HIV-1 infectionNatural killer cells(NK cells)CD39IL-10T-cell immunoreceptor with Ig and ITIM domain(TIGIT)
HIV-1 infectionNatural killer cells(NK cells)CD39IL-10T-cell immunoreceptor with Ig and ITIM domain(TIGIT)
《中国病毒学》 2026 (2)
293-302,10
This work was supported by the National Natural Science Foundation of China(NSFC,82472266 to B.S.,82272319 to H.W.),the National Key R&D Program of China(2023YFE0116000,2023YFC2308300,2023YFC2308302 to B.S.),the Beijing High-Level Innovation and Entrepreneurship Talent Support Program-Leading Talent Projects(G202512065 to B.S.),the Public Health Talent Training and Support Program of the National Disease Control and Prevention Administration(B.S.),the Scientific Research Project of Beijing Youan Hospital-CCMU 2022(BJYAYY-YN2022-18 to X.Z.),and the Beijing Key Laboratory for HIV/AIDS Research(BZ0089 to B.S.).The funders had no role in study design,data collection and analysis,decision to publish,or preparation of the manuscript.
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