1例隆林黄牛源产气荚膜梭菌的分离鉴定与药敏试验分析OA

To identify the pathogenic pathogen responsible for the illness and death of cattle on a specialized cattle farm in Longlin County,Guangxi,and to provide a scientific basis for clinical diagnosis and treatment,this study was conducted.Based on epidemiological investigations of the affected cattle,sterile samples of heart,spleen,liver,and other tissues were collected from a dead calf.A dominant bacterial strain was isolated and purified through bacterial culture,and subsequently subjected to observations of cultural characteristics,biochemical identification,and drug susceptibility testing.The results showed that the isolated strain was Clostridium perfringens.Antimicrobial susceptibility testing indicated that this strain was highly sensitive to Ceftiofur Sodium,Florfenicol,and Doxycycline,but not sensitive to Streptomycin,Kanamycin,Penicillin,Erythromycin,and Tylosin.The results demonstrate that the pathogen causing the sudden death of cattle on this farm is Clostridium perfringens,and the isolate exhibits resistance to some commonly used clinical antibiotics.Ceftiofur Sodium,Florfenicol,and Doxycycline can be recommended as the first-choice drugs for clinical prevention and control.