清补方治疗初期哺乳期乳腺炎随机对照研究OA
Randomized controlled trial of Qingbu prescription in the treatment of early lactation mastitis
目的:研究经验方清补方对比经典方瓜蒌牛蒡汤治疗初期哺乳期乳腺炎的临床疗效,探讨补益气血、清热通络之法治疗本病是否优于传统的疏肝清胃、通乳消肿疗法.方法:选取60例哺乳期乳腺炎患者纳入研究,且入组患者符合纳入标准,以随机数字表法分组:观察组(30例,清补方口服),对照组(30例,瓜蒌牛蒡汤口服).并于治疗前、治疗第7天评估临床症状评分及疼痛评分,检测两组白细胞(WBC)、中性粒细胞百分比(N%)及C反应蛋白(CRP),记录母乳喂养自我效能感简表(BSES-SF),对比清补方与瓜蒌牛蒡汤治疗哺乳期乳腺炎的临床疗效,评价治疗前后母乳喂养自信心和有效率.结果:两组治疗后各项症状评分及症状总分均低于治疗前(均P<0.05),其中观察组在缩小乳房肿块、促进乳汁分泌、缓解恶寒发热症状方面治疗效果更显著(均P<0.05);两组治愈率(观察组80.00%与对照组53.33%),观察组更优(P<0.05),且在总有效率方面观察组亦高于对照组(均P<0.05);治疗后两组WBC、N%及CRP指标均较初诊时降低(P<0.05);两组治疗后VAS疼痛评分较治疗前均降低(P<0.05);在BSES-SF评分方面,治疗后两组的评分均明显升高(P<0.05),且观察组评分增幅更大(P<0.05).结论:清补方可以显著提高初期哺乳期乳腺炎患者治愈率,改善临床症状,增强母乳喂养自信心.
Objective:To study the clinical efficacy of empirical Qingbu prescription compared with classical pre-scription Gualou Niubang decoction in the treatment of early lactation mastitis,and to explore whether the method of tonifying qi and blood,clearing heat and dredging compliaries is better than the traditional therapy of soothing the liv-er and clearing the stomach,clearing milk and reducing swelling.Methods:A total of 60 patients with lactation masti-tis were included in the study,and the enrolled patients met the inclusion criteria,and were divided into groups by random number table method:The observation group(30 cases,Qingbu prescription oral),the control group(30 ca-ses,Gualou Niubang decoction oral).Clinical symptom score and pain score were evaluated before treatment and on the 7th day of treatment,the indexes of white blood cell(WBC),neutrophil percentage(N%)and C-reactive protein(CRP)were detected,and BSES short form(BSES-SF)of breast-feeding self-efficacy was recorded.The clinical effi-cacy of Qingbu prescription and Gualou Niubang decoction in the treatment of lactation mastitis was compared,and the confidence and efficiency of breast-feeding before and after treatment were evaluated.Results:Symptom scores and total symptom scores of the two groups were lower after treatment than before treatment(all P<0.05),and the observation group had more significant therapeutic effects in reducing breast mass,promoting milk secretion,relie-ving cold and fever symptoms(all P<0.05).In terms of the cure rate of the two groups(80.00%in the observation group vs 53.33%in the control group),the observation group was better(P<0.05),and the total effective rate of the observation group was higher than that of the control group(all P<0.05).After treatment,WBC,N%the inde-xes of and CRP in 2 groups were decreased compared with those at initial diagnosis(P<0.05).VAS pain scores of both groups were lower after treatment than before treatment(P<0.05).In terms of BSES-SF scores,the scores of the two groups were significantly increased after treatment(P<0.05),and the score of the observation group in-creased more significantly(P<0.05).Conclusion:Qingbu prescription can significantly improve the cure rate of early lactation mastitis patients,improve clinical symptoms,enhance breastfeeding self-confidence.
姚孟杰;吴雪卿;冯佳梅;瞿文超;高晴倩;邵士珺;孙佳晔;谢璐
上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021上海中医药大学附属曙光医院乳腺科,上海 200021
医药卫生
哺乳期乳腺炎清补方瓜蒌牛蒡汤母乳喂养自信心乳房肿块随机对照研究
Lactation mastitisQingbu prescriptionGualou Niubang decoctionBreastfeeding Self-confidenceBreast massRandomized controlled trial
《陕西中医》 2026 (6)
772-776,5
上海市科学技术委员会科研计划项目(19401934000)上海市卫生健康委员会科研计划项目(202040254)
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