首页|期刊导航|内科理论与实践|慢性Q热合并肾功能不全1例

慢性Q热合并肾功能不全1例OA

A case of chronic Q fever complicated with renal insufficiency

中文摘要英文摘要

慢性Q热由贝纳柯克斯体感染引起,临床病例较少,合并肾功能不全的病例报道更罕见.目前国内外关于该病的报道不多,其临床特点和发病机制尚不明确.本文报道 1例临床表现为肾病综合征、肾功能受损的慢性 Q热患者,肾活检提示为膜增生性肾小球肾炎,经糖皮质激素、环磷酰胺、羟氯喹联合多西环素治疗后,其肾功能得到改善.

Chronic Q fever is caused by Coxiella burnetii infection.There are few clinical cases of chronic Q fever,and cases complicated with renal insufficiency are even more rarely reported.At present,there are few reports about this disease both domestically and internationally,and its clinical characteristics and pathogenesis remain unclear.This article reports a case of a chronic Q fever patient with clinical manifestations of nephrotic syndrome and impaired renal function,whose renal biopsy revealed membranoproliferative glomerulonephritis.After treatment with glucocorticoid,cyclophosphamide,hydroxychloroquine combined with doxycycline,the patient's renal function improved.

李一林;张春丽;沈平雁;徐静;胡晓帆;李娅

上海交通大学医学院附属瑞金医院肾内科,上海 200025||苏州市中医医院肾内科,江苏 苏州 215000上海交通大学医学院附属瑞金医院肾内科,上海 200025上海交通大学医学院附属瑞金医院肾内科,上海 200025上海交通大学医学院附属瑞金医院肾内科,上海 200025上海交通大学医学院附属瑞金医院肾内科,上海 200025上海交通大学医学院附属瑞金医院肾内科,上海 200025

医药卫生

慢性Q热肾病综合征膜增生性肾小球肾炎二代测序多西环素羟氯喹

chronic Q fevernephrotic syndromemembranoproliferative glomerulonephritisnext-generation sequencingdoxycyclinehydroxychloroquine

《内科理论与实践》 2026 (2)

167-170,4

瑞金医院广慈创新技术启航计划(GCQH2025143)

10.16138/j.1673-6087.2026.02.10

评论