肝转移瘤18F-FDG PET/CT研究进展与展望OA
Progress and prospects of 18F-FDG PET/CT in liver metastases
肝脏是肿瘤转移的常见部位,肝转移瘤常继发于结直肠癌、胰腺癌、黑色素瘤、肺癌和乳腺癌等.在所有恶性肿瘤转移中,肝转移占比近25%,肝转移患者的1年生存率为15.1%.肝转移瘤的早期诊断和精准治疗对改善患者预后至关重要.18氟-2-脱氧葡萄糖(18F-fluoro-deoxy-D-glucose,18F-FDG)PET/CT作为一种功能代谢与解剖结构相结合的影像学检查技术,在肝转移瘤的诊断、分期、治疗方案制定等方面发挥着越来越重要的作用.文章综述了近年来 18F-FDG PET/CT在肝转移瘤研究中的进展,包括在肝转移瘤诊断、鉴别诊断、治疗前评估、疗效评估、预后预测等方面的应用,与其他影像学方法比较的优劣势,在延迟成像、图像优化等技术方面的新进展,在诊断某些疾病时的陷阱,在引导放疗时的作用等.最后,总结了人工智能技术在肝转移瘤诊疗中的应用,并对 18F-FDG PET/CT应用于肝转移瘤的发展方向进行了展望.
The liver is a common site for tumor metastases.Liver metastases often occur secondary to malignancies including colorectal cancer,pancreatic cancer,melanoma,lung cancer,and breast cancer,accounting for nearly 25%of all cancer metastases,and the 1-year survival rate for all patients with liver metastases is 15.1%.Early diagnosis and precise treatment are crucial for improving patient prognosis.As an imaging technique that combines functional metabolism with anatomical structure,18F-fluoro-deoxy-D-glucose(18F-FDG)PET/CT plays an increasingly important role in the diagnosis,staging,and treatment planning of liver metastases.This article reviews recent advances in 18F-FDG PET/CT research on liver metastases,including its applications in diagnosis,differential diagnosis,pre-treatment evaluation,efficacy assessment,and prognosis prediction;its advantages and disadvantages in comparative imaging;new technological developments such as delayed imaging and image optimization;diagnostic pitfalls in certain diseases;and its role in guiding radiotherapy.Finally,it summarizes the application of artificial intelligence technology in the diagnosis and treatment of liver metastases and provides prospects on the future development directions of 18F-FDG PET/CT in this field.
孙庆;梁迪;何健
南京医科大学鼓楼临床医学院核医学科,江苏 南京 210008南京医科大学鼓楼临床医学院核医学科,江苏 南京 210008南京医科大学鼓楼临床医学院核医学科,江苏 南京 210008
医药卫生
18氟-2-脱氧葡萄糖肝转移瘤PET/CT人工智能
18F-fluoro-deoxy-D-glucoseliver metastasesPET/CTartificial intelligence
《南京医科大学学报(自然科学版)》 2026 (6)
799-808,10
国家重点研发计划(2020YFA0713800)
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