基于中脘穴艾灸联合中医推拿治疗脾胃虚弱型儿童功能性消化不良的疗效及对肠道菌群的影响OA
Effect of moxibustion combined with traditional Chinese medicine massage on functional dyspepsia of spleen and stomach weakness in children based on Zhongwan point and its effect on intestinal flora
目的 探讨中脘穴艾灸联合中医推拿治疗脾胃虚弱型儿童功能性消化不良(FD)的疗效及对肠道菌群的影响.方法 选取2024年3月至2025年3月邢台医学院第二附属医院收治的102例FD患儿作为研究对象,采用随机数字表法分为观察组和对照组,每组51例.对照组采用中医推拿进行治疗,观察组在对照组的基础上联合中脘穴艾灸进行治疗.比较2组治疗前后中医证候积分、临床疗效、尼平消化不良指数(NDI)、Bristol粪便性状评分表(BSFS)评分及肠道菌群变化情况.统计2组治疗期间不良反应发生情况.结果 治疗后,2组胃脘隐痛或痞满、喜温喜按、泛吐清水、食少或纳呆、疲乏、手足不温、便溏、舌脉中医证候积分、主症合计、次症合计、总分及 NDI、BSFS评分,以及肠杆菌、酵母样菌水平均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05).治疗后,2组乳酸杆菌、双歧杆菌水平及双歧杆菌与肠杆菌科细菌数量的比值均高于治疗前,且观察组均高于对照组,差异均有统计学意义(P<0.05).观察组治疗总有效率为94.12%,高于对照组的80.39%,差异有统计学意义(P<0.05).2组治疗期间不良反应发生情况比较,差异无统计学意义(P>0.05).结论 中脘穴艾灸联合中医推拿治疗脾胃虚弱型儿童FD能够有效降低临床证候积分,提高肠道有益菌的分布,改善肠道功能,提高患儿生活质量,联合疗效优于单一疗法.
Objective To explore the therapeutic effect of moxibustion at Zhongwan point combined with traditional Chinese medicine massage on functional dyspepsia(FD)in children with spleen and stomach weak-ness and its effect on intestinal flora.Methods A total of 102 children with FD admitted to the Second Affilia-ted Hospital of Xingtai Medical University from March 2024 to March 2025 were selected as the research ob-jects,and they were divided into observation group and control group by random number table method,with 51 cases in each group.The control group was treated with TCM massage,and the observation group was trea-ted with moxibustion at Zhongwan point on the basis of the control group.The TCM syndrome score,clinical efficacy,Nepin dyspepsia index(NDI),Bristol stool form score(BSFS)and intestinal flora changes were com-pared between the two groups before and after treatment.The occurrence of adverse reactions during treat-ment in the two groups was counted.Results After treatment,the epigastric pain or fullness,liking warmth and pressing,vomiting water,eating less or not eating,fatigue,tepid hands and feet,loose stool,TCM syn-drome scores of tongue and pulse,total score of main symptoms,total score of secondary symptoms,total score of NDI,BSFS,and the levels of Enterobius and yeast like bacteria in the two groups were lower than those before treatment,and those in the observation group were lower than those in the control group and the differences were statistically significant(P<0.05).After treatment,the levels of Lactobacillus and Bifidobac-terium and the ratio of Bifidobacterium to Enterobacteriaceae in the two groups were higher than those before treatment,and the observation group was higher than the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 94.12%,which was higher than 80.39%of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion Moxibustion at Zhongwan point combined with traditional Chinese medicine massage in the treatment of FD in children with spleen-stomach weakness can effectively reduce the clinical syndrome score,improve the distribution of intestinal beneficial bacteria,improve intestinal function and improve the quality of life of children,and the combined effect is better than single therapy.
李丹;田雪利;李桂云;冯丽娟;施磊
邢台医学院第二附属医院儿科,河北 邢台 054000邢台医学院第二附属医院儿科,河北 邢台 054000邢台医学院第二附属医院药物Ⅰ期临床试验研究室,河北 邢台 054000邢台医学院第二附属医院儿科,河北 邢台 054000河北医科大学第一医院消化内科,河北 石家庄 050023
医药卫生
功能性消化不良脾胃虚弱证儿童中脘穴艾灸推拿肠道菌群临床疗效
functional dyspepsiaspleen stomach weakness syndromechildrenZhongwan pointmoxibustionmassageintestinal floraclinical efficacy
《检验医学与临床》 2026 (11)
1480-1485,1491,7
河北省中医药管理局中医药类科学研究课题计划项目(2024007)河北省邢台市重点研发计划自筹项目(2025ZC112).
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