恶性肿瘤患儿营养不良风险筛查及其影响因素研究OA

Objective To assess the malnutrition risk in children with malignant tumors,and analyze its related influencing factors.Methods A total of 177 children aged 2 months to 17 years with malignant tumors admitted to the Department of Pediatric Hematology and Oncology,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine from November 2022 to March 2023 were enrolled.The screening tool for assessment of malnutrition in pediatrics(STAMP)was used to evaluate the children from three dimensions:disease risk,dietary intake,and growth and development.Malnutrition risk was determined according to the total STAMP score,and multivariate binary Logistic regression was used to analyze the influencing factors.Results Among the 177 children,9(5.08%)had high malnutrition risk,85(48.02%)had moderate risk,and 83(46.89%)had low or no risk.STAMP scores differed significantly by age,tumor stage,and number of chemotherapy cycles(all P<0.05).Logistic regression analysis,using a STAMP score≥2 as the cutoff for malnutrition risk,showed that age[OR(95%CI):0.14(0.02 to 0.96)],number of chemotherapy cycles[OR(95%CI):1.04(1.00 to 1.08)],and serum albumin level at admission[OR(95%CI):0.29(0.11 to 0.77)]were significantly associated with malnutrition risk(all P<0.05).Conclusion Children with malignant tumors are at high malnutrition risk,especially younger children and those with more chemotherapy cycles.Combining malnutrition risk screening with serum albumin measurement allows for early identification of malnutrition risk and timely implementation of nutritional support,thereby improving quality of life and treatment outcomes.