基于"肠道菌群-免疫轴"探讨从脾论治自身免疫性甲状腺炎OA

Autoimmune thyroiditis is a common disease of the endocrine system,with its incidence rate increasing year by year,and its accompanying symptoms seriously affecting the quality of life of patients and their families.It has been found that the gut microbiota has a close relationship with the spleen,and the balance of the gut microbiota is related to the normalization of the spleen's function.Disordered gut microbiota as a risk factor can directly or indirectly cause autoimmune thyroiditis through its metabolites and immune mechanism.The spleen plays a regulatory role in autoimmune thyroiditis,gut microbiota and immune response.Therefore,this article discusses the treatment of autoimmune thyroiditis from the perspective of"gut microbiota-immunity axis"based on the spleen theory.It is argued that the method of tonifying qi and strengthening the spleen can improve the disorder of gut microbiota,reduce the immune-inflammatory reaction,and treat autoimmune thyroiditis.