老年T2DM患者CF发生现状及相关影响因素OA

Objective To investigate the current status of cognitive frailty(CF)in elderly patients with type 2 diabetes melli-tus(T2DM),and to analyze the relationship between CF occurrence and sleep quality and psychological state in T2DM pa-tients,so as to provide a reference for clinical treatment.Methods A total of 198 elderly T2DM patients hospitalized in Cangzhou People's Hospital from May 2022 to May 2025 were selected as study participants by convenience sampling.The patients were surveyed using a general information questionnaire,the Fried's Phenotype(FP),the Montreal Cognitive As-sessment(MoCA),the Pittsburgh Sleep Quality Index(PSQI),and the Hospital Anxiety and Depression Scale(HADS).Pearson correlation analysis was used to explore the relationship between CF occurrence and sleep quality and psychological state in elderly T2DM patients;multivariate logistic stepwise regression analysis was used to analyze the influencing factors for CF occurrence in elderly T2DM patients.Results The mean FP score of the 198 elderly T2DM patients in this study was(2.63±0.82)points,and the mean MoCA score was(24.58±2.79)points.Among them,56 patients(28.28%)had CF and were included in the CF group,and the remaining 142 patients(71.72%)were included in the non-CF group.The PSQI and HADS scores in the CF group were significantly higher than those in the non-CF group(P<0.05).In elderly T2DM patients,FP score was positively correlated with PSQI and HADS scores,while MoCA score was negatively correla-ted with PSQI and HADS scores(P<0.05).The duration of T2DM in the CF group was longer than that in the non-CF group;the proportions of living alone and having≥2 types of comorbid chronic diseases,the levels of glycated hemoglobin and fasting blood glucose were higher than those in the non-CF group;and the proportion of regular exercise was lower than that in the non-CF group,with statistically significant differences(P<0.05).Multivariate logistic stepwise regression anal-ysis showed that living alone,having≥2 types of comorbid chronic diseases,elevated glycated hemoglobin,elevated PSQI score,and elevated HADS score were independent risk factors for CF occurrence in elderly T2DM patients,while regular exercise was an independent protective factor for CF occurrence(P<0.05).Conclusion Clinical attention should be paid to elderly T2DM patients who are older,live alone,have multiple comorbidities,and have poor sleep and psychological status.Early screening and assessment should be carried out.Comprehensive interventions,including strengthening health manage-ment,improving sleep and psychological status,and promoting regular exercise,can reduce the risk of CF and delay the de-cline of physical and cognitive function.