化妆品中潜在内分泌干扰物及其检测技术研究进展OA

China's economic growth and rising living standards have fueled demand for skin health and beauty,integrating cosmetics into daily life.However,their various ingredients,complex supply chains and manufacturing processes can introduce endocrine-disrupting chemicals(EDCs)at multiple stages.Compounding this risk are frequent use and multiple exposure routes such as dermal,oral,and inhalation,making EDCs a significant health concern.Systematic research is thus crucial to safeguard public health and strengthen regulatory standards.This review first described the types and hazards of EDCs in cosmetics briefly and summarized the EDCs-related sample pretreatment and detection methods reported since 2015.The advantages,limitations,and practical applicability of different techniques in cosmetic analysis were compared.Special attention was given to recent progress and representative tools in mass spectrometry.Method transferability from other matrices to cosmetics was also discussed.Finally,research prospects were proposed,covering detection technologies,mechanistic studies,combined exposure assessment,and risk evaluation.This work aimed to provide a reference for future studies on EDCs in cosmetics.