重构本草之玄参OA
Reconstruction of Chinese materia medica:Scrophulariae Radix
通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出玄参的主要功效为清热凉血,滋阴降火,解毒散结.症靶为斑疹、咽喉肿痛、便秘、咳嗽.标靶为高血糖、甲状腺结节.现代药理研究显示,玄参及其有效成分具抗炎、解热、降糖、增强免疫、保肝、抗肿瘤等多种作用.玄参苦泄滑肠而通便,脾胃虚寒、脾胃有湿、食少便溏不宜用.临床常用剂量为9~15 g.
Through investigation of ancient books and the sorting of modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of famous experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that Scrophulariae Radix mainly has the e ffects of clearing heat and cooling blood,nourishing Yin and lowering fire,and detoxifying and dispersing masses.The symptom targets are macula,sore throat,constipation and cough.The biochemical indicator targets are hyperglycemia and thyroid nodules.Modern pharmacological studies have found that Scrophulariae Radix and its active components have anti-inflammatory,antipyretic,hypoglycemic,immunomodulatory,hepatic protective,and antitumor effects.Scrophulariae Radix has bitter purgative properties that may cause diarrhea,making it unsuitable for those with spleen-stomach cold deficiency,dampness in spleen-stomach,or poor appetite and loose stools.The commonly used clinical dose is 9-15 g.
孙丹阳;李彤;高胜男
广州中医药大学深圳医院<福田>,广东 深圳 518000广州中医药大学深圳医院<福田>,广东 深圳 518000广州中医药大学深圳医院<福田>,广东 深圳 518000
医药卫生
玄参症靶标靶重构本草临床回归
Scrophulariae Radixsymptom targetbiochemical indicator targetreconstruction of Chinese materia medicaclinical verification
《长春中医药大学学报》 2026 (6)
677-679,3
国家自然基金委-中国科学院联合项目资助中西医结合创新范式战略研究(XK2023SMC003)深圳市"医疗卫生三名工程"仝小林院士中医代谢病团队项目(SZZYSM202202010)广州中医药大学深圳医院(福田)科研专项资助(GZYSY2024050)
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