展青霉素降解酶及其降解特性的研究进展OA

Given that patulin poses a significant threat to human health,its efficient degradation has become a key concern in food safety.This review summarizes the types,degradation mechanisms,and factors influencing the degradation efficiency of patulin-degrading enzymes.Patulin-degrading enzymes mainly include lipases,oxidoreductases,esterases,aldolases,aldo-keto reductases,and transferases,which exhibit distinctly different degradation characteristics.The degradation mechanisms of patulin-degrading enzymes involve hydrolysis,redox reactions,indirect oxidation and other reactions,and the degradation efficiency is influenced by multiple factors such as enzyme type,enzymatic reaction conditions,and enzyme immobilization.Currently,the application and development of targeted and highly efficient biodegradation of patulin are limited by the low biological activity and unclear degradation mechanisms of patulin-degrading enzymes.Future research will focus on the directed modification of active sites in patulin-degrading enzymes,the construction of a toxicity database for degradation products,and the in-depth exploration of degradation mechanisms,thereby enhancing their application value in the food industry and providing a reference for the safe control of mycotoxins during food processing.