No.2 Kangxianling decoction(抗纤灵二号方)protects against renal ischemia/reperfusion injury by hypoxia-inducible factor activationOA

作者：YU Kena;ZHONG Liping;LIN Xiaomeng;CHEN Jian;HE Liqun;CAI Xudong

作者单位：Department of Nephrology,Ningbo Municipal Hospital of Traditional Chinese Medicine(TCM),Affiliated Hospital of Zhejiang Chinese Medical University,Ningbo 315000,ChinaDepartment of Nephrology,Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430000,ChinaDepartment of Nephrology,Ningbo Municipal Hospital of Traditional Chinese Medicine(TCM),Affiliated Hospital of Zhejiang Chinese Medical University,Ningbo 315000,ChinaDepartment of Traditional Medicine,Shanghai Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200082,ChinaShanghai University of Traditional Chinese Medicine,Shanghai 200120,China||Department of Nephrology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200013,ChinaDepartment of Nephrology,Ningbo Municipal Hospital of Traditional Chinese Medicine(TCM),Affiliated Hospital of Zhejiang Chinese Medical University,Ningbo 315000,China

中文关键词：reperfusion injuryhypoxia-inducible factorFG-4592renal tubular injuryNo.2 Kangxianling decoction

英文关键词：reperfusion injuryhypoxia-inducible factorFG-4592renal tubular injuryNo.2 Kangxianling decoction

刊名：《中医杂志（英文版）》 2026 (2)

页码/页数：306-315,10

基金：National Natural Science Foundation of China:Research on The Pathogenesis of Renal Micro Syndrome Accumulation in Chronic Renal Failure through Mammalian Target of Rapamycin Signaling Pathway and the Anti-fibrotic Effect of Kangxianling Decoction on Gene Knockout Mice(No.81373615)Zhejiang Natural Science Foundation of China:Mechanism Study of Wenyangxiaozheng Decoction Alleviating Cellular Senescence and Ameliorating Renal Fibrosis by Regulating the Phosphatidylinositol 3-kinase/Protein Kinase B(LBY24H290002)

DOI：10.19852/j.cnki.jtcm.2026.02.004