首页|期刊导航|中外医学研究|探讨胱抑素C(CysC)与尿微量白蛋白(U-mALB)联合检测对糖尿病肾病的早期诊断价值

探讨胱抑素C(CysC)与尿微量白蛋白(U-mALB)联合检测对糖尿病肾病的早期诊断价值OA

To Explore the Early Diagnostic Value of Combined Detection of Cystatin C(CysC)and Urinary Microalbumin(U-mALB)for Diabetic Nephropathy

中文摘要英文摘要

目的:探讨胱抑素C(CysC)与尿微量白蛋白(U-mALB)联合检测在诊断糖尿病肾病中的实际效用和重要性.方法:选取于 2023 年 1 月—2024 年 1 月龙岩市第一医院收治的 50 例未出现糖尿病肾病的健康受检者作为第Ⅰ组,50 例未出现肾病的糖尿病患者作为第Ⅱ组,50 例糖尿病肾病患者作为第Ⅲ组.针对这三组的样本,分别进行了胱抑素 C 和尿微量白蛋白的专项检测,以获取相应的数据结果.结果:经检测和分析,发现第Ⅲ组的 U-mALB 和 CysC 浓度明显高于第Ⅰ组以及第Ⅱ组,差异有统计学意义(P<0.05).进一步观察 U-mALB 和 CysC 的阳性率时,发现这一比率在第Ⅰ组、第Ⅱ组和第Ⅲ组之间逐渐上升,差异有统计学意义(P<0.05).结论:对于糖尿病肾病患者而言,检测 CysC 和 U-mALB 具有较高的临床价值.这两项指标是早期诊断肾脏损伤的敏感指标,有助于够帮助医生在早期阶段进行干预和治疗.在糖尿病肾病的诊疗过程中,早期采用 CysC 与 U-mALB 的联合检测,对于其诊断与治疗具有一定的实际意义.

Objective:To explore the practical utility and importance of cystatin C(CysC)and urinary microalbumin(U-mALB)combined detection in the diagnosis of diabetic nephropathy.Method:50 healthy subjects were selected who were admitted to Longyan First Hospital from January 2023 to January 2024 and did not have diabetic nephropathy as group Ⅰ,50 diabetic patients without kidney disease as group Ⅱ,and 50 patients with diabetic nephropathy as group Ⅲ.For these three groups of samples,the special detection of cystatin C and urinary microalbumin was carried out to obtain the corresponding data results.Result:After detection and analysis,it was found that the concentrations of U-mALB and CysC in group Ⅲ were significantly higher than those in group Ⅰ and group Ⅱ.Further observation of the positive rate of U-mAlb and CysC showed that the rate gradually increased between group Ⅰ,group Ⅱ and group Ⅲ,and the differences were statistically significant(P<0.05).Conclusion:For patients with diabetic nephropathy,it is concluded that the detection of CysC and U-mALB has high clinical value.These two indicators are sensitive indicators for early diagnosis of kidney injury,and help doctors to intervene and treat in the early stage.In the diagnosis and treatment of diabetic nephropathy,early detection of CysC and U-mALB has certain practical significance for its diagnosis and treatment.

张晓君;范玉琳;陈婷歆;邓佳英

龙岩市第一医院 福建 龙岩 364000龙岩市第一医院 福建 龙岩 364000龙岩市第一医院 福建 龙岩 364000龙岩市第一医院 福建 龙岩 364000

胱抑素C尿微量蛋白联合检测糖尿病肾病

Cystatin CUrinary microproteinCombined detectionDiabetic nephropathy

《中外医学研究》 2026 (12)

68-70,3

10.14033/j.cnki.cfmr.2026.12.018

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