维持性血液透析患者发生导管相关性血流感染的影响因素分析OA
Analysis of Factors Influencing Catheter-Related Bloodstream Infections in Patients Undergoing Maintenance Hemodialysis
目的:分析长期维持性血液透析患者导管相关性血流感染(CRBSI)发生情况及其相关影响因素.方法:回顾性分析 2023 年 2 月—2025 年 5 月于莆田九十五医院长期维持性血液透析的 142 例终末期肾脏病患者的临床资料,依据患者是否发生CRBSI 进行分组,分为感染组与未感染组,并通过单因素及多因素分析相关影响因素.结果:142 例维持性血液透析患者中,有 26例患者出现 CRBSI.单因素分析显示,性别、身体质量指数、高血压、置管部位与终末期肾脏病长期血液透析患者发生 CRBSI 无关(P>0.05),年龄、糖尿病、导管留置时间、植入导管类型、无菌操作标准与长期维持性血液透析患者发生CRBSI 有关(P<0.05).将CRBSI 是否发生作为因变量,将上述差异有统计学意义的因素作为自变量进行赋值.多因素分析显示,年龄>60 岁、合并糖尿病、导管留置时间>2 周、植入导管类型为长期、无菌操作不标准是导致长期维持性血液透析患者发生CRBSI 的独立危险因素(P<0.05).结论:维持性血液透析患者CRBSI发生风险仍然较高,临床应结合相关危险因素采取相应的预防性对策进行干预,以降低感染风险.
Objective:To analyze the incidence of catheter-related bloodstream infections(CRBSI)and associated factors among patients undergoing long-term maintenance hemodialysis.Method:Clinical data of 142 end-stage renal disease patients undergoing long-term maintenance hemodialysis at Putian 95th Hospital from February 2023 to May 2025 were retrospectively analyzed.Patients were grouped into the infection group and the non-infection group based on whether they developed CRBSI,and the related influencing factors were analyzed through univariate and multivariate analyses.Result:Among 142 maintenance hemodialysis patients,26 developed CRBSI.Univariate analysis revealed that gender,body mass index,hypertension,and catheter insertion site were not associated with CRBSI occurrence in long-term hemodialysis patients with end-stage renal disease(P>0.05).Age,diabetes,catheter indwelling duration,implanted catheter type,and adherence to aseptic technique standards were significantly associated with CRBSI occurrence(P<0.05).Using CRBSI occurrence as the dependent variable and the aforementioned statistically significant factors as independent variables,multivariate analysis revealed that age>60 years,diabetes mellitus,catheter indwelling duration>2 weeks,long-term catheter type,and non-standard aseptic technique were independent risk factors for CRBSI in long-term maintenance hemodialysis patients(P<0.05).Conclusion:The risk of CRBSI remains high among patients undergoing maintenance hemodialysis.Clinicians should implement preventive interventions tailored to relevant risk factors to reduce infection risk.
吴德花;郑丽花;吴华贞;郑书萍
福建省莆田九十五医院 福建 莆田 351100福建省莆田九十五医院 福建 莆田 351100福建省莆田九十五医院 福建 莆田 351100福建省莆田九十五医院 福建 莆田 351100
终末期肾脏病维持性血液透析导管相关性血流感染影响因素预防性护理对策
End-stage renal diseaseMaintenance hemodialysisCatheter-related bloodstream infectionInfluencing factorsPreventive nursing interventions
《中外医学研究》 2026 (12)
9-12,4
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