乙型肝炎肝硬化食管胃静脉曲张破裂出血硬化治疗后1年内再出血危险因素分析OA
Analysis of Risk Factors for Rebleeding within One Year after Sclerotherapy for Esophageal and Gastric Variceal Bleeding in Hepatitis B Cirrhosis
目的:研究乙型肝炎肝硬化食管胃底静脉曲张破裂出血 EGVB 患者内镜下硬化治疗后 1 年内再次出血的危险因素.方法:收集宁夏回族自治区人民医院在 2020 年 1 月—2022 年 12 月接诊的乙型肝炎肝硬化患者的临床资料,根据术后 1 年内是否出现再次出血分为再出血组(60 例)和未出血组(65 例),对两组情况进行统计分析.结果:口服非选择性β受体阻滞剂(NSBB)、总胆红素(TBIL)、白蛋白(ALB)、凝血酶原时间(PT)、国际标准化比值(INR)、静脉曲张程度皆为再次出血的危险因素(P<0.05).经过多因素非条件 logistic 回归分析显示 TBIL 和 PT 为硬化治疗后再次出血的独立危险因素.结论:服用非选择性 β 受体拮抗剂能够有效降低再出血率.TBIL、ALB、PT、INR、静脉曲张程度是 EGVB 患者内镜治疗后再次出血的危险因素.TBIL 和 PT 为再出血的独立危险因素.
Objective:To study the risk factors of rebleeding within one year after endoscopic sclerotherapy in patients with esophageal and gastric variceal bleeding(EGVB)due to hepatitis B cirrhosis.Method:Clinical data of patients with hepatitis B cirrhosis admitted to the People's Hospital of Ningxia Hui Autonomous Region from January 2020 to December 2022 were collected.They were divided into the rebleeding group(60 cases)and the non-bleeding group(65 cases)based on whether there was rebleeding within one year after the operation.Statistical analysis was conducted on the conditions of the two groups.Result:Oral non-selective beta-blockers(NSBB),total bilirubin(TBIL),albumin(ALB),prothrombin time(PT),international normalized ratio(INR),and the degree of varicose veins were all risk factors for rebleeding(P<0.05).Multivariate unconditional logistic regression analysis showed that TBIL and PT were independent risk factors for rebleeding after sclerotherapy.Conclusion:Taking non-selective beta-blockers can effectively reduce the rebleeding rate.TBIL,ALB,PT,INR and the degree of varicose veins are risk factors for rebleeding in patients with EGVB after endoscopic treatment.TBIL and PT are independent risk factors for rebleeding.
李玉珍;穆蕊;马守成
宁夏回族自治区人民医院 宁夏 银川 750002宁夏回族自治区人民医院 宁夏 银川 750002宁夏回族自治区人民医院 宁夏 银川 750002
乙型肝炎肝硬化食管胃静脉曲张出血内镜下硬化治疗再次出血
Hepatitis B cirrhosisEsophagogastric variceal bleedingEndoscopic sclerotherapyRebleeding
《中外医学研究》 2026 (11)
113-115,3
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