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中医药治疗支气管扩张用药规律的R语言数据挖掘研究OA

Data Mining Study on Medication Rules of Traditional Chinese Medicine in Treating Bronchiectasis Based on R Language

中文摘要英文摘要

目的 应用数据挖掘技术分析中医药治疗支气管扩张的用药规律,为临床辨证用药提供参考.方法 回顾性收集2021年1月1日至2025年8月31日在安徽中医药大学第一附属医院呼吸内科住院的支气管扩张患者的中药处方,运用R语言进行挖掘.结果 共涉及303首处方,190味中药,总频次4 064.四气中寒、平性频次最高;五味中甘、苦、辛频次最高;归经中肺、胃、脾、心、肝经频次居前5.中药种类中,化痰止咳平喘药、清热药、补虚药、利水渗湿药、止血药使用频次居前5.药物关联规则显示,芦根-桔梗、芦根-薏苡仁-桔梗、黄芩-芦根-薏苡仁-桔梗分别是二、三、四阶支持度最高的组合.提炼出2个核心处方,分别针对痰热壅肺或气阴两虚夹痰型患者的治疗.结论 数据挖掘从真实世界客观揭示中医药治疗支气管扩张的用药特点,为临床辨证论治提供了一定的参考依据.

Objective:To analyze the medication rules of traditional Chinese medicine(TCM)in the treatment of bronchiectasis based on data mining technology,and to provide references for clinical syndrome differentiation and medication.Methods:TCM prescriptions of inpatients with bronchiectasis in the Department of Respiratory Medicine,The First Affiliated Hospital of Anhui University of Chinese Medicine from January 1,2021 to August 31,2025 were retrospectively collected,and data mining was performed using R language.Results:A total of 303 prescriptions involving 190 Chinese medicinal herbs were included,with a total frequency of 4 064.Among the four natures,cold and neutral herbs had the highest frequencies;among the five flavors,sweet bitter and pungent herbs ranked the top;among meridian tropisms,lung,stomach,spleen,heart and liver meridians ranked the top five.In terms of TCM categories,phlegm-resolving,cough-relieving and asthma-relieving herbs,heat-clearing herbs,tonifying herbs,diuresis-promoting and dampness-eliminating herbs,and hemostatic herbs ranked the top five in usage frequency.Association rule analysis showed that the herb pairs with the highest support for two-,three-,and four-item combinations were Phragmitis Rhizoma-Platycodonis Radix,Phragmitis Rhizoma-Coicis Se-men-Platycodonis Radix,and Scutellariae Radix-Phragmitis Rhizoma-Coicis Semen-Platycodonis Radix,respec-tively.Two core prescriptions were extracted,targeting patients with"phlegm-heat obstructing lung"or"qi-yin de-ficiency complicated with phlegm"respectively.Conclusion:Data mining objectively reveals the medication char-acteristics of TCM in the treatment of bronchiectasis in the real world,and provides a certain reference for clinical syndrome differentiation and treatment.

黄鹤;滕港;张念志

安徽中医药大学第一附属医院,安徽 合肥 230031安徽中医药大学第一附属医院,安徽 合肥 230031安徽中医药大学第一附属医院,安徽 合肥 230031

医药卫生

支气管扩张中医药R语言处方特点

BronchiectasisTraditional Chinese medicineR languagePrescription characteristics

《中国中医急症》 2026 (5)

511-515,527,6

国家自然科学基金项目(82174312)安徽省科技厅临床医学研究转化专项(202304295107020104)国家中医优势专科(肺病科)建设项目(国中医药医政函[2024]90号)

10.3969/j.issn.1004-745X.2026.05.003

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