Berberine Ameliorates Angiotensin Ⅱ-Induced Endothelial Dysfunction by Blocking AT1R,Inhibiting PDE4b and Activating AKT/eNOS PathwayOA
Berberine Ameliorates Angiotensin Ⅱ-Induced Endothelial Dysfunction by Blocking AT1R,Inhibiting PDE4b and Activating AKT/eNOS Pathway
ZHANG Ting-yue;ZHAO Bi-ning;WU Hao-wen;ZHANG You-you;LI Jiang;LIU Qi-ming;LIU Li-mei;KANG Ji-hong
Department of Cardiovascular Medicine,the Second Xiangya Hospital of Central South University,Changsha(410011),ChinaDepartment of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University,Beijing(100191),ChinaDepartment of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University,Beijing(100191),ChinaDepartment of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University,Beijing(100191),ChinaDepartment of Cardiovascular Medicine,the Second Xiangya Hospital of Central South University,Changsha(410011),ChinaDepartment of Cardiovascular Medicine,the Second Xiangya Hospital of Central South University,Changsha(410011),ChinaDepartment of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University,Beijing(100191),ChinaDepartment of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University,Beijing(100191),China
angiotensin Ⅱ type 1 receptorberberineendothelial dysfunctionhypertensionphosphodiesterase 4b
angiotensin Ⅱ type 1 receptorberberineendothelial dysfunctionhypertensionphosphodiesterase 4b
《中国结合医学杂志（英文版）》 2026 (6)
536-544,9
Supported by the National Natural Science Foundation of China(Nos.82171634,81873475)and the Beijing Natural Science Foundation Project(No.7242085)
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