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"主客浑受"理论及其在系统性红斑狼疮中的运用OA

Exploration on the theory of'Zhu Ke Hun Shou'and its application in systemic lupus erythematosus

中文摘要英文摘要

"主客浑受"理论发源于《黄帝内经》,经过吴又可《温疫论》"主客交"理论的发展,于《湿热病篇》被薛生白正式提出,是指六淫、疫气、久病之热毒、瘀血等客邪入于人体阴分,导致正虚邪恋、胶固难解的一种病机状态.笔者运用"主客浑受"理论阐述了系统性红斑狼疮(SLE)的病因病机为素体主气不足,热毒、瘀血、痰饮等客邪耗伤,治疗当遵循泻客补主、解毒祛瘀、滋阴护本的原则,并根据SLE各个阶段中正邪主次的不同分别论治,对于受累的不同脏腑则根据相应脏腑之主气以及客邪变化辨证施治,以切实提高SLE的诊治水平.

The theory of'Zhu Ke Hun Shou'originated from Huangdi Neijing,and was formally proposed by XUE Shengbai in Shire Bingpian after the development of the theory of'Zhu Ke Jiao'in Wenyi Lun by WU Youke,referring to a disease state in which six climatic exopathogens,epidemics,toxic heat,blood stasis,and other Ke Xie due to chronic disease that invade the yin fen of the human body,leading to the deficient vital qi and lingering of pathogen,which is difficult to be resolved.The author used the theory of'Zhu Ke Hun Shou'to explain the etiology and pathogenesis of systemic lupus erythematosus(SLE)as the deficiency of the Zhu Qi of the origin body,and the depletion of the Ke Xie such as warm-heat and poisonous evils,stasis of blood,phlegm and drinks,etc.The treatment should follow the principles of purging Ke Xie and replenishing Zhu Qi,detoxification of the poisonous evils to eliminate stasis,and nourishment of yin to protect the root cause.In addition,the treatment should be based on the primary and secondary between the Zhu Qi and Ke Xie in the different stages of SLE,and the differences in the affected internal zang-fu organs should be recognized and treated according to the changes of the Zhu Qi and Ke Xie,which will provide inspiration and thoughts for the clinical treatment of SLE.

杨泽;吴彦佐;刘景群;金萌;李正富;范永升

浙江中医药大学第二临床医学院,杭州 310053浙江中医药大学第二临床医学院,杭州 310053浙江中医药大学第二临床医学院,杭州 310053浙江中医药大学第二临床医学院,杭州 310053浙江中医药大学附属第二医院,杭州 310005浙江中医药大学附属第二医院,杭州 310005

主客浑受系统性红斑狼疮《黄帝内经》薛生白《湿热病篇》

Zhu Ke Hun ShouSystemic lupus erythematosus(SLE)Huangdi NeijingXUE ShengbaiShire Bingpian

《中华中医药杂志》 2026 (5)

1338-1341,4

科技部国家重点研发计划项目子课题(No.2018YFC1704102),浙江省中青年临床名中医培养项目(No.浙中医药[2022]7号)

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